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| MBIO2009 | Enzymology | 3+0+0 | ECTS:4 | | Year / Semester | Fall Semester | | Level of Course | Short Cycle | | Status | Elective | | Department | DEPARTMENT of CHEMISTRY and CHEMICAL PROCESS TECHNOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face, Group study | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Melike YILDIRIM AKATIN | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | to teach the general properties of enzyme catalysis mechanisms and to examine their role in metabolism and regulation |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | understands basic level of theoretical knowledge about enzymes. | | | | LO - 2 : | categorize enzymes. | | | | LO - 3 : | describe the clinical and physiological properties of the enzymes used in clinical diagnosis . | | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| The structure and properties of enzymes , nomenclature and classification of enzymes , enzyme kinetics, activators , inhibitors, enzyme inhibition, allosteric enzymes, isoenzymes , factors affecting enzyme activity, the use of enzymes, enzyme activity assay methods, blood levels of the enzyme and detection methods |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | The structure and properties of enzymes | | | Week 2 | Nomenclature and classification of enzymes | | | Week 3 | Enzyme kinetics | | | Week 4 | Enzyme kinetics | | | Week 5 | Activators | | | Week 6 | Inhibitors | | | Week 7 | Enzyme inhibition | | | Week 8 | Enzyme inhibition | | | Week 9 | Ara sınav | | | Week 10 | Allosteric enzymes | | | Week 11 | Isoenzymes | | | Week 12 | Factors affecting enzyme activity | | | Week 13 | The use of enzymes | | | Week 14 | Enzyme activity assay methods | | | Week 15 | Blood levels of the enzyme and detection methods | | | Week 16 | Final exam | | | |
| 1 | Nelson, D.L., Cox, M.M. , 2005. Lehninger Principles of Biochemistry, W.H. Freeman and Company, New York. | | | 2 | Keha, E., Küfrevioğlu, Ö.İ. 2004; Biyokimya, Aktif Yayınevi, Ankara. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 18.11.2016 | 1 | 50 | | End-of-term exam | 17 | 12.01.2017 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 2 | 14 | 28 | | Arasınav için hazırlık | 4 | 8 | 32 | | Arasınav | 1 | 1 | 1 | | Dönem sonu sınavı için hazırlık | 4 | 6 | 24 | | Dönem sonu sınavı | 1 | 1 | 1 | | Total work load | | | 128 |
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