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| BYF5001 | Biophysics I | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Compulsory | | Department | DEPARTMENT of BIOPHYSICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | Prof. Dr. İsmail Abidin
Dr. Öğr. Üyesi Harun Başoğlu | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The aim of the course is to examine and learn biophysical events at the molecular and cellular level. It is aimed to explain the events in the cell with the principles of physics and to solve the related problems. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | explain the energy cycle in living systems | 1,2,3 | | | PO - 2 : | explain the forces affecting particle transport in living systems and the state of equilibrium. | 1,2,3 | | | PO - 3 : | count the passive properties of the cell membrane and their results. | 1,2,3 | | | PO - 4 : | Calculate ion movements at a given concentration and potential in the cell | 1,2,3 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Lecture deals with biophysical events at the molecular and cell level. Information and information theory, Biomolecules and their physical properties, Bioenergetics, Thermodynamic Concepts, Energy transfer in biological systems, Cell membranes and movement in membranes, Forces affecting ion movements and related rules, Ion channels and gating mechanisms. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Subject and scope of Biophysical Science | | | Week 2 | Bioenergetic | | | Week 3 | Bioenergetic | | | Week 4 | Biophysical properties of water and biological molecules | | | Week 5 | The cell and cell membrane | | | Week 6 | Diffusion, diffusion at membranes | | | Week 7 | pyhsical and electrical properties of the cell membrane | | | Week 8 | Midterm | | | Week 9 | Electric potential difference and particle transport at the cell membrane | | | Week 10 | Ionic channels at the cell membrane | | | Week 11 | Ionic eqilibrium and Nerst equation | | | Week 12 | Active transport, ionic pumps and exchange proteins | | | Week 13 | Capacitive properties of the cell membrane and the concept of time constant | | | Week 14 | Passive properties of the cell membrane and the concept of the space constant | | | Week 15 | Electrical equivalent circuit model of the cell membrane | | | Week 16 | Final exam | | | |
| 1 | Biyofizik, Prof. Dr. Ferit PEHLİVAN. Palme Yayınevi 1997 | | | |
| 1 | Bütünleştirilmiş Molekülsel ve Hücresel Biyofizik, Çeviri Editörü Prof. Dr. Rüstem NURTEN, İstanbul Kitapevi, 2013 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | | | 30 | | Homework/Assignment/Term-paper | 12 | | | 20 | | End-of-term exam | 16 | | | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | | | | |
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