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| MBTL5044 | Genetics in Medicine | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of BIOTECHNOLOGY (INTERDISCIPLINARY) | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Doç. Dr. Selcen ÇELİK UZUNER | | Co-Lecturer | | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Understand the features of cancer cells in cell cyle and apoptosis | 1 | | | PO - 2 : | Understand the transformations in cancer cells towards metastasis and angiogenesis | 1 | | | PO - 3 : | Distinguish the immune system responses that prevent and induce cancer formation. | 1 | | | PO - 4 : | Understands the extent of cancer stem cells. | 1 | | | PO - 5 : | Comprehends mutations, chromosomal changes and epigenetic modifications observed in cancer cells. | 1 | | | PO - 6 : | Knows current cancer diagnosis and treatment methods. | 1 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| It includes understanding human gene and genome structure, human genetic variations (mutations and polymorphisms), chromosomal, genetic, molecular and biochemical bases of diseases. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Gene, chromosome and genome structure | | | Week 2 | Cell cycle, apoptosis, necrosis | | | Week 3 | Tumor supressor genes and oncogenes | | | Week 4 | Metastasis | | | Week 5 | Angiogenesis | | | Week 6 | Cancer stem cells | | | Week 7 | Epigenetic changes in cancer | | | Week 8 | Immune system and cancer | | | Week 9 | Cancer diagnosis | | | Week 10 | Cancer therapy | | | Week 11 | Nutritions and cancer | | | Week 12 | Drug resistance in cancer | | | Week 13 | Post-transciptional changes in cancer | | | Week 14 | Students presentations | | | Week 15 | | | | Week 16 | | | | |
| 1 | Thompson & Thompson Genetics in Medicine (Thompson and Thompson Genetics in Medicine) 8th Edition | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | | 1 | 30 | | In-term studies (second mid-term exam) | 15 | | 1 | 20 | | End-of-term exam | 16 | | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 16 | 48 | | Arasınav | 1 | 1 | 1 | | Dönem sonu sınavı | 1 | 1 | 1 | | Total work load | | | 50 |
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