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| MBTL5040 | Fermentation Technologies | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of BIOTECHNOLOGY (INTERDISCIPLINARY) | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Dr. Öğr. Üyesi Uğur UZUNER | | Co-Lecturer | | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | | It is aimed to provide students with the latest developments in the fields of food and fermentation biotechnology, current applications and innovative technologies applied during these applications. It is also aimed to contribute to the spread of low-cost and sustainable fermentation processes in our country by contributing to the development of innovative and molecular strategies to find solutions to the difficulties encountered in fermentation processes. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Gains knowledge of current fermentation processes | 1,2,4,5 | | | PO - 2 : | Knows the important parameters of fermentation processes and understands their effects on the process. | 1,2,4,5 | | | PO - 3 : | Be aware of innovations in fermentation technologies | 1,2,4,5 | | | PO - 4 : | Can design laboratory-scale fermentation processes | 1,2,4,5 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| An introduction to fermentation processes; Microbial growth kinetics; The isolation, preservation and improvement of industrial important microorganisms; Media for industrial fermentation; Steriization; Development of inocula for industrial fermentation; Design of a fermenter; Insturmentation and control; Aeration and agitation; The recovery and purification of fermentation product; Effluent treatement; Fermentation economics |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | An introduction to fermentation processes | | | Week 2 | Microbial growth kinetics | | | Week 3 | The isolation and improvement of industrially important microorganisms | | | Week 4 | Batch and Fed-batch Fermentation | | | Week 5 | Open and Continuous fermentation systems | | | Week 6 | Recombinant DNA Technology for Fermentation | | | Week 7 | Media for industrial fermentations | | | Week 8 | Postgenomic era?the influence of genomics, transcriptomics,
and fluxomics on the improvement of primary metabolite producers | | | Week 9 | Mid-Term Exam | | | Week 10 | Feedback İnhibition | | | Week 11 | Improvement of Strains Producing Secondary Biosynthetic Products | | | Week 12 | Sterilization of Fermenters | | | Week 13 | Culture preservation and inoculum development, Instrumentation and control | | | Week 14 | Downstream Processing steps | | | Week 15 | Student Seminar | | | Week 16 | Final Exam | | | |
| 1 | Peter F. Stanbury, Allan Whitaker, and Stephen J. Hall. Principles of Fermentation Technology. 3rd Edition. Butterworth-Heinemann ELSEIVER 2017. ISBN: 978-0-08-099953-1 | | | |
| 1 | Biotechnology for Beginners 2nd Edition Arnold L. Demain. Academic Press. ELSEIVER 2017. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 25.11.2021 | 90 | 30 | | Presentation | 15 | 13.01.2022 | 90 | 20 | | End-of-term exam | 16 | 21.01.2022 | 90 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Arasınav için hazırlık | 3 | 6 | 18 | | Arasınav | 3 | 1 | 3 | | Uygulama | 3 | 6 | 18 | | Ödev | 3 | 6 | 18 | | Proje | 3 | 4 | 12 | | Kısa sınav | 3 | 6 | 18 | | Dönem sonu sınavı için hazırlık | 3 | 6 | 18 | | Dönem sonu sınavı | 3 | 1 | 3 | | Total work load | | | 192 |
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