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| MBGL7080 | @ | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of MOLECULAR BIOLOGY and GENETICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Dr. Öğr. Üyesi Cihan İNAN | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | It is aimed for students to have knowledge about viruses and replication mechanisms, to understand viral adhesion and entry into the cell, and to learn cell surface receptors and their interactions with viral proteins. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Learning the definition and classification of viruses | 2,6 | 1,5, | | PO - 2 : | Understanding virus-host interactions and being able to comment on the mechanism of infection based on viral genetic material. | 2,6 | 1,5, | | PO - 3 : | Ability to create interaction maps between viral adhesion proteins and host receptors | 2,6 | 1,5, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| General information about viruses, viral infection cycle, Viral genetic genomes, Structure of viruses, Viral attachment and entry, DNA Hybridization methods, Viral Adhesion Introduction PPI systems and BioID, Protein production methods, Fundamentals of infection, Antivirals, Viral vaccines, Virus-host interactions, current article analyzes |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | What is Virus? | | | Week 2 | Infection cycle | | | Week 3 | Viral genetics and genomes | | | Week 4 | Structure of the viruses | | | Week 5 | Viral attachment and entry | | | Week 6 | DNA hybridisation methods | | | Week 7 | Viral attachment and entry: PPI Systems and BioID | | | Week 8 | Mid-term exam | | | Week 9 | Protein production methods | | | Week 10 | Infection principles | | | Week 11 | Antivirals | | | Week 12 | Viral Vaccines | | | Week 13 | Article analysis in virus-host interactions 1 | | | Week 14 | Article analysis in virus-host interactions 2 | | | Week 15 | Student presentations | | | Week 16 | Final Exam | | | |
| 1 | Principles of Virology: Molecular Biology, Pathogenesis, and Control of Animal Viruses. S. J. Flint, V. R. Racaniello, L. W. Enquist, V. R. Rancaniello, A. M. Skalka.
| | | 2 | Virus-Host Interactions Methods and Protocols Ed: John Susanne M. Bailer & Diana Lieber ISBN: 978-1-62703-600-9 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | | 1 | 30 | | Presentation | 14 | | 1 | 20 | | End-of-term exam | 16 | | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 15 | 45 | | Sınıf dışı çalışma | 4 | 14 | 56 | | Arasınav için hazırlık | 4 | 7 | 28 | | Arasınav | 1 | 1 | 1 | | Ödev | 2 | 14 | 28 | | Dönem sonu sınavı için hazırlık | 3 | 15 | 45 | | Dönem sonu sınavı | 1 | 1 | 1 | | Total work load | | | 204 |
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