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| MBGL5041 | Mathematical Calculations in Molecular Biology and Biotechnology | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of MOLECULAR BIOLOGY and GENETICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Doç. Dr. Selcen ÇELİK UZUNER | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The aim of this course is to help researchers/students using molecular biology and biotechnology techniques understand what type of calculations to use and why. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Knows the scientific notation of numbers and their significant digits. Can make calculations of solutions and mixtures. | 3 | 1,5, | | PO - 2 : | Can calculate cell growth and determine nucleic acid amounts and purities. | 3 | 1,5, | | PO - 3 : | Knows the logic of PCR and QPCR and can make calculations regarding reactions. | 3 | 1,5, | | PO - 4 : | Makes calculations regarding recombinant DNA and proteins and knows the logic of centrifugation. | 3 | 1,5, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Research in the field of biotechnology and molecular biology requires a huge amount of calculations. The results of a dataset form the basis of the working text. One mistake by choosing the wrong type of equation can turn the success of a research project or weeks of study and research into complete failure. It may be possible to calculate the time required for a sample to grow or the synthesis of multiple variables in the environment in which you are testing your sample. The content of this course covers the calculations used in different but widely used molecular biology techniques. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Scientific nomination and metrics | | | Week 2 | Solutions and mixtures | | | Week 3 | Cell growth | | | Week 4 | Nucleic acid identification | | | Week 5 | PCR calculations | | | Week 6 | QPCR calculations | | | Week 7 | Mid-term exam | | | Week 8 | Recombinant DNA calculations | | | Week 9 | Protein analysis | | | Week 10 | Student presentations | | | Week 11 | Centrifugation | | | Week 12 | Forensic science analyses | | | Week 13 | Repeating | | | Week 14 | Final exam | | | Week 15 | | | | Week 16 | | | | |
| 1 | Moleküler Biyoloji ve Biyoteknoloji İçin Matematiksel Hesaplamalarpalme yayıncılık Frank H. Stephenson, ISBN: 9786053559825,2018 | | | |
| 1 | Temel Moleküler Biyoloji ve Genetik Teknikleri, Ceren Canatar, Furkan Ayaz Atlas Akademi | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 7 | | 1 | 30 | | Presentation | 10 | | 1 | 20 | | End-of-term exam | 14 | | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Arasınav için hazırlık | 3 | 7 | 21 | | Arasınav | 2 | 1 | 2 | | Uygulama | 1 | 14 | 14 | | Ödev | 3 | 2 | 6 | | Dönem sonu sınavı için hazırlık | 5 | 14 | 70 | | Dönem sonu sınavı | 3 | 1 | 3 | | Total work load | | | 200 |
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