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| FZY 619 | Advanced Mucle Physiology | 2+2+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Compulsory | | Department | DEPARTMENT of PHYSIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face, Group study, Practical | | Contact Hours | 14 weeks - 2 hours of lectures and 2 hours of practicals per week | | Lecturer | Dr. Öğr. Üyesi Ömer Faruk KALKAN | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | Aim of this lecture is to teach students mechanisms of skeletal and smooth muscle contractility, and to discover the underlying design principles of the neuromuscular physiology system and understand the adaptive ability of the neuromuscular system. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | gain grounding knowledge on molecular physiological and biochemical properties of muscle contraction | 1,2,3,4,5,6 | 1,2,3 | | PO - 2 : | contractile apparatus at cellular level | 1,2,3,4,5,6 | 1,2,3 | | PO - 3 : | energy sources and pathways | 1,2,3,4,5,6 | 1,2,3 | | PO - 4 : | the involvement of musculoskeletal system in exercise | 1,2,3,4,5,6 | 1,2,3 | | PO - 5 : | mechanical, chemical and electrical events during skeletal and smooth muscle contraction | 1,2,3,4,5,6 | 1,2,3 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Muscle Types, Physiologic Anatomy of the Skeletal Muscle, Properties of Contraction, Molecular Basics of Contraction, Energy Usage of the Contraction, Rigor Mortis, Neuromuscular Conduction, Muscle Action Potential, Smooth Muscle Physiology, Molecular Basics of Smooth Muscle, Contraction, Neuromuscular Junction, Smooth Muscle, Factors Regulating Smooth Muscle Contraction |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Physiological anatomy and histology of muscles | | | Week 2 | molecular structure of muscles | | | Week 3 | principles of muscle electrophysiology | | | Week 4 | molecular mechanism of contraction in skeletal muscle | | | Week 5 | neuromuscular junction | | | Week 6 | EMG | | | Week 7 | Mechanics of skeletal muscle contractility | | | Week 8 | Mid-term exam | | | Week 9 | Energy of skeletal muscle contractility | | | Week 10 | Mechanisms of fatique | | | Week 11 | molecular mechanism of contraction in smooth muscle | | | Week 12 | regulation of smooth muscle contraction | | | Week 13 | Isometric and isotonic contractions | | | Week 14 | isometric contractility practices in isolated tissue bath | | | Week 16 | Final exam | | | |
| 1 | Muscle Physiology and Biochemistry, Shoichi Imai, Makoto Endo, Iwao Ohtsuki, 1999, Springer, New York | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | | 2 | 30 | | Oral exam | 14 | | 1 | 20 | | End-of-term exam | 16 | | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Laboratuar çalışması | 2 | 5 | 10 | | Uygulama | 2 | 2 | 4 | | Ödev | 3 | 3 | 9 | | Proje | 10 | 2 | 20 | | Total work load | | | 43 |
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