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| MBG4000 | Cancer Biology and Genetics | 3+0+0 | ECTS:4 | | Year / Semester | Spring Semester | | Level of Course | First Cycle | | Status | Compulsory | | Department | DEPARTMENT of MOLECULAR BIOLOGY and GENETICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Doç. Dr. Selcen ÇELİK UZUNER | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Understand the difference between normal and cancerous cells | 1,3,11 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| It includes understanding the molecular and genetic bases of cancer and its difference from healthy cells. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Definition of cancer | | | Week 2 | Introduction to differences between normal and cancer cells | | | Week 3 | Resistance mechanisms against apoptosis in cancer | | | Week 4 | Independence from growth factors and Escaping from tumour suppressing factors in cancer | | | Week 5 | Invasion and metastasis | | | Week 6 | Angiogenesis | | | Week 7 | Unlimited growth potential and telomeres | | | Week 8 | Tumour microenvironment | | | Week 9 | Tumour suppressor genes and oncogenes | | | Week 10 | DNA repair in cancer and repair mechanisms in therapy | | | Week 11 | Epigenetics, micro RNAs and cancer | | | Week 12 | Cancer stem cells | | | Week 13 | Regulation of cell cycle and cancer | | | Week 14 | | | | Week 15 | | | | Week 16 | | | | |
| 1 | Kanser Moleküler Biyolojisi - Prof Dr. Yusuf Baran Kısayol Yayıncılık 2018 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | | 2 | 30 | | Homework/Assignment/Term-paper | 10
11 | | 2 | 20 | | End-of-term exam | 14 | | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Ödev | 2 | 2 | 4 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 48 |
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