|
|
| MBG2004 | Fundamentals of Genetics | 3+0+0 | ECTS:5 | | Year / Semester | Spring Semester | | Level of Course | First Cycle | | Status | Compulsory | | Department | DEPARTMENT of MOLECULAR BIOLOGY and GENETICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Dr. Öğr. Üyesi Cihan İNAN | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To teach students almost all of the basic genetic concepts and to provide a basis for students in all areas of classical Mendelian genetics. For students who successfully complete this course, the ultimate goal of this course is to equip students with basic knowledge of Mendel's basic laws and knowledge about the contributions of modern genetics to this field, and to understand the further topics of the genetics. In order to achieve this, students will be able to develop their problem-solving and analytical thinking abilities and will be taught how geneticists solve problems and make new discoveries. In addition, it is to equip students with sufficient information about sexuality, sexual related, cytoplasmic inheritance, population genetics, evolutionary genetics and molecular genetics. For students who successfully complete this course, the ultimate goal of this course is to enable students to solve problems, to think analytically, to understand the power of DNA technology, to know the basic concepts of genetics and molecular biology, to be knowledgeable in all areas of genetics, to be able to comprehend advanced topics of cell and molecular biology it is to provide |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Understanding Mendelian laws 1 and 2 and their relationship to cytogenetics | 3,11,12 | 1, | | LO - 2 : | Find results of crossings using Punnet | 3,11,12 | 1,2 | | LO - 3 : | Be able to apply chi square test on crossover results | 3,11,12 | 1,2 | | LO - 4 : | Be able to design an experiment to identify genotypes using test crossings and explain the experiment | 3,11,12 | 1,2 | | LO - 5 : | Compares incomplete dominance with coercion and predicts their inheritance mode | 3,11,12 | 1,2 | | LO - 6 : | Be able to describe multiple ancestors, multiple loci and a gene's effect on more than one character | 3,11,12 | 1,2 | | LO - 7 : | To explain a single gene genetics, be able to draw and show relationships in the genealogy | 3,11,12 | 1,2 | | LO - 8 : | Be able to create genetic maps | 3,11,12 | 1,2 | | LO - 9 : | Be able to solve quantitative problems of genetics | 3,11,12 | 1,2 | | LO - 10 : | Identify the sex of individuals in normal and abnormal chromosomal structures | 3,11,12 | 1,2 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| History, basic concepts and inheritance pattern, test organisms and variation, chromosomal basis of inheritance, organization and gene interactions, statistical analysis, gene transfer in organisms, gene linkage, recombination, and chromosome mapping, tissue incompatibility and self sterility, quantitative genetics and phenotypic expression, assays determination, sex-linked and sex-influenced inheritance, chromosome number and structure changes and mutation of extranuclear genes, population genetics and evolution, genetic development, immunogenetics, genetic engineering. |
| |
| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | History of Genetics and experimental animals used in genetics | | | Week 2 | Monohybrid crossing | | | Week 3 | Chromosomes and Cell division | | | Week 4 | Deviations from dihybrid crossing and Mendel's ratios | | | Week 5 | Gene Connections | | | Week 6 | Multiple Allels | | | Week 7 | Polygenic Inheritance | | | Week 8 | Phenotypic Expression | | | Week 9 | Mid-term exam | | | Week 10 | Gender detection | | | Week 11 | Inheritance of gender-related characteristics | | | Week 12 | Changes in the number of chromosomes | | | Week 13 | Changes in the structure of chromosomes | | | Week 14 | Cytoplasmic Inheritance | | | Week 15 | Population Genetics | | | Week 16 | Final exam | | | |
| 1 | Genetik Kavramlar-On birinci baskıdan çeviri/Klug, Spencer, Spencer, Palladino/Palme Yayınevi | | | |
| 1 | Genetik Ders Notları, Belduz vd, Biyoloji Bölümü, TRABZON, 2013 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | 8. hafta | | 50 | | End-of-term exam | 16 | 16. hafta | | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 2 | 14 | 28 | | Laboratuar çalışması | 0 | 0 | 0 | | Arasınav için hazırlık | 4 | 7 | 28 | | Arasınav | 2 | 1 | 2 | | Uygulama | 0 | 0 | 0 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 0 | 0 | 0 | | Proje | 0 | 0 | 0 | | Kısa sınav | 0 | 0 | 0 | | Dönem sonu sınavı için hazırlık | 5 | 5 | 25 | | Dönem sonu sınavı | 2 | 1 | 2 | | Diğer 1 | 5 | 5 | 25 | | Diğer 2 | 2 | 1 | 2 | | Total work load | | | 154 |
|