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| MBG3001 | Molecular Genetics | 4+0+0 | ECTS:6 | | Year / Semester | Fall Semester | | Level of Course | First Cycle | | Status | Compulsory | | Department | DEPARTMENT of MOLECULAR BIOLOGY and GENETICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 4 hours of lectures per week | | Lecturer | Doç. Dr. Selcen ÇELİK UZUNER | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | Aim of this course is to understand the properties of nucleic acid molecules which are the basis of genetic information of organisms, to understand chromosome organization and packaging in prokaryotic and eukaryotic organisms, to understand and compare how procaryotic and eukaryotic organisms perform processes that are essential for multiplication and gene expression such as DNA replication, transcription and translation |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | The properties of nucleic acids which are fundamental building blocks of molecular biology and genetics. | 11,12 | 1 | | LO - 2 : | Be able to understand the organization of chromosome and the bases of DNA replication during cell division in prokaryotic and eukaryotic organisms. | 11,12 | 1 | | LO - 3 : | To understand and compare the common and organismal stages of transcription and translation mechanisms of prokaryotic and eukaryotic organism stages of gene expression. | 11,12 | 1 | | LO - 4 : | To be able to grasp molecular mechanisms through the form, to express the given mechanism with the form. | 11,12 | 1 | | LO - 5 : | To be able to make inferences about existing problems using basic information, to be able to discuss inferences based on scientific evidence. | 11,12 | 1 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| General Information, DNA, transcription, translation, gene expression in prokaryotes; gene expression in eukaryotes, Mutations and DNA repair, Developmental Genetics, Cancer, Neurogenetics, Epigenetics, Gene therapy, DNA Forensic Science, Recombinant DNA technology and genetic engineering, Omics
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Genetic code and Transcription | | | Week 2 | Translation and Proteins | | | Week 3 | Mutations - DNA repair and Transposition | | | Week 4 | Gene expression in prokaryotes | | | Week 5 | Gene expression in prokaryotes in eukaryotes | | | Week 6 | Developmental Genetics | | | Week 7 | Cancer | | | Week 8 | Quantitative Genetics | | | Week 9 | Mid-term exam | | | Week 10 | Neurogenetics | | | Week 11 | Epigenetics | | | Week 12 | Gene therapy | | | Week 13 | DNA Forensic Medicine | | | Week 14 | Student Presentations | | | Week 15 | Recombinant DNA Technology and Genetic Engineering and Omics | | | Week 16 | Final exam | | | |
| 1 | Genetik Kavramlar, Klug, Cummings, Spencer, Palladino. / On birince Baskıdan Çeviri, Editörler: Sibel Sümer, Leyle Açık ve Münir Tuncer, Palme Yayınevi, 2018 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | | | 30 | | In-term studies (second mid-term exam) | 10 | | | 20 | | End-of-term exam | 16 | | | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Arasınav için hazırlık | 5 | 2 | 10 | | Arasınav | 2 | 1 | 2 | | Ödev | 5 | 1 | 5 | | Dönem sonu sınavı için hazırlık | 8 | 2 | 16 | | Dönem sonu sınavı | 2 | 2 | 4 | | Total work load | | | 65 |
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