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| BIO 628 | Hormone Biochemistry | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of MEDICAL BIOCHEMISTRY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The main purpose of the course is to examine structure, synthesis, function, and action mechanism of hormones |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | classificate the hormones | 1,2,3,4,5 | 1,3 | | PO - 2 : | explain structure, synthesis, and transport of hormones | 1,2 | 1,3 | | PO - 3 : | explain the action mechanisms of hormones | 1,2 | 1,3 | | PO - 4 : | evaluate the use of hormones in medicine | 4 | 1,3 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Introduction to hormone biochemistry (hormonal amins, peptid, protein, and glycoprotein hormons, steroid hormons, mecanism of hormone action, hormone receptors, organisation of the endocrine system) Hormones of hypothalamus and hypophysisHormones of adrenal glands (hormones of cortex and medulla) Hormones of tyroid gland (structure-activity of tyroid hormones, tyroid hormone synthesis, transport and metabolism of tyroid hormones, biological action of tyroid hormones) Hormones of reproductive system (hormones of testes and ovaries) |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Introduction and classification of hormones | | | Week 2 | structure, synthesis, storage, release, transport, and breakdown of hormones | | | Week 3 | hormone receptors, cell- surface receptors, ıntracellular receptors | | | Week 4 | organisation of endocrine system | | | Week 5 | action mechanisms of hormones (postreceptor actions of hormones) | | | Week 6 | action mechanisms of hormones (postreceptor actions of hormones) | | | Week 7 | hypothalamus hormones | | | Week 8 | Mid-term exam | | | Week 9 | pituitary hormones | | | Week 10 | adrenal cortex hormones | | | Week 11 | adrenal medulla hormones | | | Week 12 | tyroid hormones, structure and synthesis | | | Week 13 | transport and metabolism of tyroid hormones | | | Week 14 | reproductive system hormones (testes and ovarie) | | | Week 15 | | | | Week 16 | End-of-term exam | | | |
| 1 | Bhagavan, N.V. 2002; Medical Biochemistry, Academic Press, Fourth Edition, Canada | | | 2 | Burtis, A.B., Achwood, E.R., Bruns, D.E. 2006; TIETZ Textbook of Clinical Chemistry and Molecular Diagnostics,Elsevier Inc. USA | | | 3 | Baynes, W.B. 2005; Medical Biochemistry, Elsevier Mosby, Fourth Edition, China | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | 18/11/2016 | 2 | 30 | | Homework/Assignment/Term-paper | 12 | 09/12/2016 | 4 | 20 | | End-of-term exam | 16 | 10/01/2017 | 3 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Sınıf dışı çalışma | 4 | 14 | 56 | | Laboratuar çalışması | 0 | 0 | 0 | | Uygulama | 0 | 0 | 0 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 0 | 0 | 0 | | Proje | 0 | 0 | 0 | | Diğer 1 | 0 | 0 | 0 | | Diğer 2 | 0 | 0 | 0 | | Total work load | | | 56 |
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