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DIS 343Pharmacology2+0+0ECTS:4
Year / SemesterFall Semester
Level of CourseSecond Cycle
Status Compulsory
Prerequisites and co-requisitesNone
Mode of DeliveryFace to face, Group study
Contact Hours14 weeks - 2 hours of lectures per week
LecturerProf. Dr. Nuri İhsan KALYONCU
Co-LecturerProf. Dr. Ersin YARIŞ, Prof. Dr. Nuri İhsan KALYONCU, Assoc. Prof. Dr. Sabri Murat KESİM.
Language of instructionTurkish
Professional practise ( internship ) None
The aim of the course:
The course aims to provide students general knowledge about the basic principles of pharmacology, and give information about the drugs used in the treatment of different diseases.
Learning OutcomesCTPOTOA
Upon successful completion of the course, the students will be able to :
LO - 1 : describe and comment on the absorption, bioavailability, distribution and elimination of the drugs, and the drug-receptor interaction. 1,2,71,
LO - 2 : comment on the physiology of autonomic nervous system, and to classify the drugs used in the therapy of the diseases related with the autonomic nervous system. 1,2,71,
LO - 3 : describe and comment on the drugs used in cardiovascular diseases. 1,2,71,
LO - 4 : comment on the physiology of central nervous system, and to classify the drugs used in the therapy of the diseases related with the central nervous system. 1,2,71,
LO - 5 : describe and comment on the general principles and properties of chemotherapeutics. 1,2,71,
CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome

Contents of the Course
General knowledge about the physiopathological mechanisms and the drugs used in the treatment of the diseases. Basic principles of PharmacologyRoutes of drug administrationThe pharmaceutical forms of drugsAbsorption and distribution of drugs Metabolism and elimination of drugs Receptors and drug-receptor interactionDose-concentration-effect interaction Mechanisms of drug action Factors affecting the drug actionInteraction between the drugsToxic effects of drugsDrug allergiesThe teratogenic, mutagenic and carcinogenic effects of drugsProstaglandins and leukotrienesOther autacoidsHistamine and antihistaminic drugs Serotonin and serotonin antagonist drugs Angiotensine and antagonist drugsIntroduction to Autonomic Nervous System Pharmacology Parasympathomimetic-Parasympatholytic drugs Sympathomimetic-Sympatholytic drugs Drugs used to treat congestive heart failure Drugs used to treat angina pectoris Antihypertensive drugs. Drugs used in disorders of coagulation Drugs used to treat arrhythmiasHypolipidemic drugsIntroduction to Central Nervous System Pharmacology Drug addictionLocal anesthetics General anesthetics Sedatives-hypnoticsAlcoholsAntidepressant drugsAnticonvulsant drugsNeuroleptic drugsAntiparkinson drugsNon-steroidal anti-inflammatory analgesicsNarcotic analgesics Drugs used to treat migraine Principles of Antimicrobial Drug UsePenicillinCephalosporinesOther Beta- Lactam antibioticsChloramphenicolsMacrolides TetracyclinesAminoglycosides SulfonamidesFloroquinolonesDrug used to treat tuberculosis and lepraeAntianerobic drugsMiscellaneous antibiotics Antiseptics and dezenfektanlar Antiviral drugs and drugs used to treat AIDS General principles of drug poisoning Prescription
Course Syllabus
 WeekSubjectRelated Notes / Files
 Week 1Introduction Pharmaceutical forms of drugs
 Week 2Drug applications Mechanisms of drug action
 Week 3Absorbtion and distribution of drugs
 Week 4Biotransformation and elimination of drugs I
 Week 5Biotransformation and elimination of drugs II
 Week 6Factors of changing the action of drugs İnteractions between drugs
 Week 7Receptors and drug-receptor interaction Dose-concentration-action interaction
 Week 8Toxic actions of drugs; drug allergies
 Week 9Tetratogenic, mutagenic and carcinogenic actions of drugs
 Week 10Serotonin and antagonists of serotonin Histamin and antihistaminics
 Week 11Prostaglandins and leukotriens Angiotensin and its antagonists
 Week 12Introduction to Autonomic Nervous System
 Week 13Cempatomimetic drugs
 Week 14Cempatolitic drugs
 Week 15midterm exam
 Week 16Parasempatomimetic drugs; Parasempatolitic drugs
 Week 17Antihypertensive drugs
Textbook / Material
1Kayaalp OS. 2006; Rasyonel Tedavi Yönünden Tıbbi Farmakoloji,Türkiye
Recommended Reading
Method of Assessment
Type of assessmentWeek NoDate

Duration (hours)Weight (%)
Mid-term exam 15
End-of-term exam 33 28/06/2024 1 50
Student Work Load and its Distribution
Type of workDuration (hours pw)

No of weeks / Number of activity

Hours in total per term
Yüz yüze eğitim 2 14 28
Sınıf dışı çalışma 4 14 56
Arasınav için hazırlık 4 4 16
Arasınav 0 0 0
Dönem sonu sınavı 0 0 0
Total work load100