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| FAR 511 | Pharmacokinetics | 1+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Compulsory | | Department | DEPARTMENT of PHARMACOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 1 hour of lectures per week | | Lecturer | -- | | Co-Lecturer | Asst. Prof. Dr. Mine Kadıoğlu Duman | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The course aims to provide the students a general knowledge on parameters and pharmacokinetic events (absorption, distribution, biotransformation, excretion) on the basis of drug action, to enable them to understand the importance of pharmacokinetic properties of drugs. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | learn what pharmacokinetics is. | 1,3,5 | 1,6 | | PO - 2 : | learn what absorption mechanisms of the drugs are | 1,3,5 | 1,6 | | PO - 3 : | learn what disrtribution mechanisms of the drugs are. | 1,3,5 | 1,6 | | PO - 4 : | learn what biotrransformation mechanisms of the drugs are. | 1,3,5 | 1,6 | | PO - 5 : | to learn what excretion mechanismsare of the drugs are | 1,3,5 | 1,6 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| There are four steps of pharmacokinetics: absorption, distribution, biotransformation and excretion. Drug action is affected directly by these events dependent to the concentration reached at the target tissue. The knowledge about the pharmacokinetics and the functions of the organs that play a role in pharmacokinetics will help the students to understand the effect of possible problems in disease conditions on pharmacokinetics, and also will help to overcome these problems. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Pharmacokinetics-1: Drugs absorption | | | Week 2 | Drug across membranes mechanism-1 | | | Week 3 | Drug across membranes mechanism-2 | | | Week 4 | Drug across membranes mechanism-3 | | | Week 5 | Pharmacokinetics-2: Drug disttribution-1 | | | Week 6 | Drug disttribution-2 | | | Week 7 | Drug disttribution-3 | | | Week 8 | Mid-term exam | | | Week 9 | Pharmacokinetics-3: Metabolism of Drug-1 | | | Week 10 | Metabolism of Drug-2 | | | Week 11 | Metabolism of Drug-3 | | | Week 12 | Second Midterm Exam | | | Week 13 | Pharmacokinetics-4:Excretion of Drugs-1 | | | Week 14 | Excretion of Drugs-2 | | | Week 16 | End-of-term exam | | | |
| 1 | Kayaalp,SO.2009; Rasyonel Tedavi Yönünden Tıbbi Farmakoloji., Pelikan Yayıncılık, Ankara | | | |
| 1 | Brunton, LL (editör), Süzer, Ö (çeviri editörü). 2009;Goodman and Gilman,Tedavinin Farmakolojik Temeli, Nobel tıp Yayınevi, Ankara | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8
12 | | 1
1 | 50 | | End-of-term exam | 16 | | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 0 | 0 | 0 | | Laboratuar çalışması | 5 | 14 | 70 | | Arasınav için hazırlık | 2 | 14 | 28 | | Arasınav | 2 | 14 | 28 | | Uygulama | 1 | 2 | 2 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 0 | 0 | 0 | | Proje | 0 | 0 | 0 | | Kısa sınav | 0 | 0 | 0 | | Dönem sonu sınavı için hazırlık | 4 | 14 | 56 | | Dönem sonu sınavı | 1 | 1 | 1 | | Diğer 1 | 0 | 0 | 0 | | Diğer 2 | 0 | 0 | 0 | | Total work load | | | 213 |
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