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| FAR 521 | Mechanisms of Drug Action and Drug Toxicity | 2+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | Assoc. Prof. Dr. Murat Kesim | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The course aims to provide the students a general knowledge on the basic mechanisms that are used in drug action, the toxic effects observed during this drug action and the basic mechanisms of these toxic effects, to enable them to understand the mechanisms of action and adverse effects of drugs. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | list the general knowledge on the basic mechanisms that are used in drug actio | 1,2,3,5,6 | 1 | | PO - 2 : | know the details of the basic mechanisms that are used in drug actio | 1,2,3,5,6 | 1 | | PO - 3 : | list the general knowledge on the toxic effects observed during this drug actio | 1,2,3,5,6 | 1 | | PO - 4 : | list the general knowledge on the basic mechanisms of these toxic effects. | 1,2,3,5,6 | 1 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Basics of drug action
Mechanisms of drug action
Dose-concentration relationship
Dose-action and concentration-action relationship
Receptor and drug-receptor relationship
Factors altering the actions of drugs
Basic concepts of toxicology |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Basic mechanisms for drug action (1) | | | Week 2 | Basic mechanisms for drug action (2) | | | Week 3 | Dose concept and calculation for drugs | | | Week 4 | Concentration concept and calculation for drugs | | | Week 5 | Relationship between dose and concentration (1)
| | | Week 6 | Relationship between dose and concentration (2)
| | | Week 7 | Relationship between dose-effect and concentration-effect (1) | | | Week 8 | Mid-term exam | | | Week 9 | Relationship between dose-effect and concentration-effect (2) | | | Week 10 | Relationship between drugs and receptors (1) | | | Week 11 | Relationship between drugs and receptors (2) | | | Week 12 | second midterm exam | | | Week 13 | Postreceptor processes (1)
| | | Week 14 | Postreceptor processes (2) | | | Week 15 | General backup | | | Week 16 | End-of-term exam | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8
12 | | 1
1 | 50 | | End-of-term exam | 16 | | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 12 | 14 | 168 | | Arasınav için hazırlık | 10 | 2 | 20 | | Arasınav | 1 | 2 | 2 | | Dönem sonu sınavı için hazırlık | 10 | 1 | 10 | | Dönem sonu sınavı | 1 | 1 | 1 | | Total work load | | | 229 |
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