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| TBI6051 | CELL AND MOLECULAR BIOLOGY | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of MEDICAL BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Ersan KALAY | | Co-Lecturer | Associate Prof Dr. Tuba DİNÇER
Dr. Faculty Memberi Gökhan YILDIZ | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To have knowledge about advanced concepts and subjects based on basic knowledge of cell biology and molecular biology. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Explain the molecular structure of the cell. | 1,2 | 1,3, | | PO - 2 : | Explain the structure and functions of cell-cell and cell-environment interactions. | 1,2 | 1,3, | | PO - 3 : | Explain the mechanisms by which cellular disorders cause diseases. | 1,2 | 1,3, | | PO - 4 : | Explain the life cycle of the cell. | 1,2 | 1,3, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| 1. Biomolecules
2. Cell membrane
3. Transport across cell memrane and its abnormalities
4. The cell skeleton and its abnormalities
5. Cell-cell interactions and its abnormalities
6. Cell-ECM ınteractions and its abnormalities
7. Organelles (ER, Golgi apparatus, lysosome) and biology of organelle disorders
8. Organelles (mitochondria, peroxsisome) and biology of organelle disorders
9. Organelles (ribosome, centrosome) and biology of organelle disorders
10. Cell division
11. Stem cell
12. Cell differentiation
13. Cell senescence
14. Cell death (Apoptosis, Otophagy, Necrose) |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Biomolecules | | | Week 2 | Cell membrane | | | Week 3 | Transport from cellular memrane and related disorders | | | Week 4 | The cell skeleton and associated disorders | | | Week 5 | Cell-cell interactions and related disorders | | | Week 6 | Cell-ECM interactions and associated disorders | | | Week 7 | Organelles (ER, Golgi Apparatus, lysosome) and biology of organelle disorders | | | Week 8 | Midterm | | | Week 9 | Organelles (mitochondria, peroxsisome) and biology of organelle disorders | | | Week 10 | Organelles (Ribosome, centrosome) and biology of organelle disorders | | | Week 11 | Cell division | | | Week 12 | Stem cell | | | Week 13 | Cellular differentiation | | | Week 14 | Cellular senescence | | | Week 15 | Cell death (Apoptosis, Autophagy, Necrose) | | | Week 16 | End of term exam | | | |
| 1 | Geoffrey M. Cooper (Editör), THE CELL: A MOLECULAR APPROACH, EIGHTH INTERNATIONAL EDITION, Oxford Publishing Limited, 2019, ISBN: 9781605358635 | | | 2 | Ersan KALAY, Neşe ATABEY, Melek ÖZTÜRK (Çeviri Editörleri), Hücre: Moleküler Yaklaşım, Sekizinci Baskı, Ankara Nobel Tıp Kitabevleri, 2021, ISBN: 78-625-7146-84-5 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | | | | | | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 5 | 14 | 70 | | Arasınav için hazırlık | 4 | 5 | 20 | | Arasınav | 3 | 1 | 3 | | Ödev | 4 | 7 | 28 | | Dönem sonu sınavı için hazırlık | 4 | 6 | 24 | | Dönem sonu sınavı | 3 | 1 | 3 | | Total work load | | | 190 |
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