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| TBI6033 | Immunogenetics | 2+0+2 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of MEDICAL BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face, Lab work | | Contact Hours | 14 weeks - 2 hours of lectures and 2 hours of laboratory per week | | Lecturer | Prof. Dr. Ersan KALAY | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The course aims to provide the students with a general knowledge on immunity, MHC genes and transplantation. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | identify human immun system | 8 | 1 | | PO - 2 : | identify MHC genes | 9 | 1,2 | | PO - 3 : | HLA tissue typing | 11 | 1,4 | | PO - 4 : | identify transplantation genetics | 12 | 1,3,6 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Immune systemMajor organs and cell of immune systemMHC GenesPolymorphismsMHC receptorsTissue typing and NomenclatureTransplantation HLA ? Related diseasesHLA and AnthropologyCytokines Tissue typing Techniques |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | What is the immunity ? | | | Week 2 | Major organs and cell of immune system | | | Week 3 | The genetics of Blood and serum proteins | | | Week 4 | Immune system genes and Immunoglobins | | | Week 5 | MHC genes and receptors | | | Week 6 | HLA Tissue Typing | | | Week 7 | The fields of Tissue typing | | | Week 8 | Mid-term exam | | | Week 9 | HLA and transplantation | | | Week 10 | Bone Marrow Transplantation | | | Week 11 | Solid organ transplantation | | | Week 12 | Lymphocyte Cross-match and Panel reactive Anticor | | | Week 13 | HLA related diseases | | | Week 14 | Cytokine gene polymorphism | | | Week 16 | End-of-term exam | | | |
| 1 | Lechler R, warrens A. 2000; HLA in Health and Disease, Academic Press, San Diego | | | |
| 1 | http://www.ncbi.nlm.nih.gov/ | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 1 | 8 | 1,5 | 30 | | Homework/Assignment/Term-paper | 1 | 14 | 1 | 20 | | End-of-term exam | 1 | 16 | 1,5 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Laboratuar çalışması | 2 | 14 | 28 | | Arasınav için hazırlık | 5 | 7 | 35 | | Arasınav | 2 | 1 | 2 | | Ödev | 15 | 1 | 15 | | Proje | 16.5 | 1 | 16.5 | | Kısa sınav | 1 | 7 | 7 | | Dönem sonu sınavı için hazırlık | 4 | 7 | 28 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 161.5 |
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