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| TBI6034 | Population Genetics | 2+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of MEDICAL BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Doç. Dr. Tuba DİNÇER | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The course aims to provide the students with a inherited disorders and the population genetics. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | identify "what is the population | 14 | 1 | | PO - 2 : | identify gene pool and Hardy-Weinberg equality | 8 | 1,2 | | PO - 3 : | identify population genetic factors | 25 | 1,6 | | PO - 4 : | identify genetic diseases of populations | 27 | 1,6 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Population and Hardy-Weinberg equalityGene poolMutationPolimorphismHuman genome projectAllel and haplotype analysisGenetic drift/Founder effectsBottle-neck hipothesisGene flowNatural selectionGeoraphy and the populationMultifactorial disordersFilogenetik analysis |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | What is the population ? | | | Week 2 | Hardy-Weinberg equilibrium | | | Week 3 | Gene pool, Mutation and Polymorphism | | | Week 4 | Human genom projects | | | Week 5 | İntrinsic and exintrisic factorf of Population genetics | | | Week 6 | Alleles and haplotype frequencies | | | Week 7 | Genetic drift, founder effect and Bottle-neck hypothesis | | | Week 8 | Mid-term exam | | | Week 9 | Gene flow | | | Week 10 | Population and marriage | | | Week 11 | Naturel selection | | | Week 12 | Population and geography | | | Week 13 | Multifactorial disorders | | | Week 14 | The distribution of genetic disorders | | | Week 16 | End-of-term exam | | | |
| 1 | http://www.ncbi.nlm.nih.gov/ | | | |
| 1 | Pasternak JJ. 1998; An Introduction to Human Molecular Genetics. Fitzgerald Science Press, Bethesda, Maryland | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 1 | 8 | 1,5 | 30 | | Homework/Assignment/Term-paper | 1 | 14 | 1 | 20 | | End-of-term exam | 1 | 16 | 1,5 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 1 | 14 | 14 | | Arasınav için hazırlık | 4.5 | 7 | 31.5 | | Arasınav | 2 | 1 | 2 | | Ödev | 15 | 1 | 15 | | Proje | 16.5 | 1 | 16.5 | | Kısa sınav | 1 | 7 | 7 | | Dönem sonu sınavı için hazırlık | 5 | 7 | 35 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 151 |
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