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| TBI5047 | The Medical Biology and Genetics II | 2+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Compulsory | | Department | DEPARTMENT of MEDICAL BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | Prof. Dr. Figen CELEP-EYÜPOĞLU, Yrd. Doç. Dr. Tuba DİNÇER, Yrd. Doç. Dr. Bayram TORAMAN | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The aim of this cours is to provide information to studends about structure and function of genetic material and molecular bases of genetic diseases |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | explain the structure of RNA and RNA | 5 | 1 | | PO - 2 : | explain the differences between DNA and RNA | 5 | 1 | | PO - 3 : | explain DNA replication | 5 | | | PO - 4 : | explain gene expression | 6 | 1 | | PO - 5 : | explain point mutation and point mutation types | 10 | 1 | | PO - 6 : | explain inheritance tpye | 10 | | | PO - 7 : | explain chromosomes | 9 | 1 | | PO - 8 : | explain chromosomal anomalies | 9 | 1 | | PO - 9 : | explain chromosomal disease types | 9 | 1 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| 1. Structure of DNA and RNA
2. Synthesis of DNA and RNA
3. Protein synthesis
4. Genome organisation
5. Gen structure function and regülation
6. Mutations
7. Chromosome structure
8. Chromosomal anomalies
9. Chromosomal diseases
10. Epigentic mechanisms |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Structure of nucleic acides | | | Week 2 | DNA replication | | | Week 3 | RNA synhesis (Transcription) | | | Week 4 | Protein synthesis (Translation) | | | Week 5 | Point mutations | | | Week 6 | DNA repair mechanisms | | | Week 7 | Mid-term exam | | | Week 8 | Inheritance patterns | | | Week 9 | Chromosome | | | Week 10 | Chromosomal anomalies | | | Week 11 | Chromosomal diseases | | | Week 12 | Chromosomal diseases | | | Week 13 | Sitogenetic methods | | | Week 14 | Pronatal diagnosis | | | Week 15 | Epigenetics | | | Week 16 | End-of-term exam | | | |
| 1 | Lodish,A., Matsudaira, P,. Darnell.J., et.al: 2005,Molecular Cell Biology W.H. Freeman and Company. | | | 2 | Pasternak. JJ, 1999, An Introduction to Human molecular genetics. FSP, Fitzgerald. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 7 | | | 30 | | Presentation | 12 | | | 20 | | End-of-term exam | 16 | | | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 2 | 14 | 28 | | Laboratuar çalışması | 0 | 0 | 0 | | Arasınav için hazırlık | 7 | 7 | 49 | | Arasınav | 3 | 1 | 3 | | Uygulama | 2 | 1 | 2 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 4 | 10 | 40 | | Proje | 2 | 10 | 20 | | Kısa sınav | 0 | 0 | 0 | | Dönem sonu sınavı için hazırlık | 7 | 7 | 49 | | Dönem sonu sınavı | 3 | 1 | 3 | | Diğer 1 | 0 | 0 | 0 | | Diğer 2 | 0 | 0 | 0 | | Total work load | | | 222 |
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