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| HIS6012 | Modern stereological methods | 2+0+2 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of HISTOLOGY and EMBRYOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face, Lab work , Practical | | Contact Hours | 14 weeks - 2 hours of lectures and 2 hours of laboratory per week | | Lecturer | -- | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To learn modern stereological methods |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Be able to say design based stereological methods
| 3,4,5 | 1,4,5 | | PO - 2 : | Be able to tell volume calculation at microscopic images | 3,4,5 | 1,4,5 | | PO - 3 : | Be able to tell dissector and its microscopical applications | 3,4,5 | 1,4,5 | | PO - 4 : | Be able to tell application of Cavalieri method on microscopic images | 3,4,5 | 1,4,5 | | PO - 5 : | Be able to tell the fractionators and its microscopical applications | 3,4,5 | 1,4,5 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Modern design based stereological methods
Volume calculation at microscopic images
Dissector and its microscopical applications
Application of Cavalieri method on microscopic images
The fractionators and its microscopical applications |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | The history and development of the modern stereological methods.
| | | Week 2 | Basic principles of modern stereological methods. | | | Week 3 | Volume calculation at light microscopic images
| | | Week 4 | Volume calculation at electron microscopic images
| | | Week 5 | Volume ratio calculations at light microscopic images
| | | Week 6 | Volume ratio calculations at electron microscopic images
| | | Week 7 | Slice thickness calculations at light microscopic images
| | | Week 8 | Mid-term exam | | | Week 9 | Slice thickness calculations at electron microscopic images
| | | Week 10 | Archimed principles and applications | | | Week 11 | The fractionators and its microscopical applications
| | | Week 12 | Lab exam | | | Week 13 | Dissector and its microscopical applications | | | Week 14 | Application of Cavalieri method on light and electron microscopic images | | | Week 16 | End-of-term exam | | | |
| 1 | Howard CV, Reed MG. 1998. Unbiased Stereology: Three dimensional measurement in microscopy. Oxford: Bios Scientific Publishers; | | | |
| 1 | Hayat, M.A., 2000. Principles and Techniques of Electron Microscopy. Biological Applications, 4th edition, 543pp. Cambridge University Press. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | | 2 | 30 | | Practice | 12 | | 2 | 20 | | End-of-term exam | 16 | | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 13 | 26 | | Arasınav için hazırlık | 25 | 1 | 25 | | Arasınav | 2 | 1 | 2 | | Ödev | 40 | 1 | 40 | | Dönem sonu sınavı için hazırlık | 30 | 1 | 30 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 125 |
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