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| BIY7331 | Proteins | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Sabriye ÇANAKÇI | | Co-Lecturer | Prof. Dr. Ali Osman BELDÜZ | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To inform students about synthesis, posttranslational modifications, evulations, physical interactions with proteins and the other molecules, conformations, degradations and enzyme catalysis of the protein |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | describe the structure of proteins | 1,2,5 | 1,5 | | PO - 2 : | explain biosynthesis of proteins | 1,2,5 | 1,5 | | PO - 3 : | explain posttranslational modifications and evulations of proteins | 1,2,5 | 1,5 | | PO - 4 : | explain physical interactions with proteins and the other molecules | 1,2,5 | 1,5 | | PO - 5 : | explain degradations of protein and enzyme catalysis | 1,2,5 | 1,5 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Chemical properties of polypeptides, biosynthesis of proteins, evulutionary and genetic origins of protein sequences, physical interactions that determine the properties of proteins, conformational properties of polypeptide chains, the folded conformations of globular proteins, proteins in solution and in membranes, Interactions with other molecules, enzyme catalysis, degradation. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Chemical properties of polypeptides | | | Week 2 | Biosynthesis of proteins | | | Week 3 | Biosynthesis of proteins | | | Week 4 | Evolutionary and genetic origins of protein sequences | | | Week 5 | Evolutionary and genetic origins of protein sequences | | | Week 6 | Physical interactions that determine the properties of proteins | | | Week 7 | Physical interactions that determine the properties of proteins | | | Week 8 | Conformational properties of polypeptide chains | | | Week 9 | Mid-term exam | | | Week 10 | The folded conformations of globular proteins | | | Week 11 | Student Seminar | | | Week 12 | Student Seminar | | | Week 13 | Interactions with other molecules | | | Week 14 | Enzyme catalysis | | | Week 15 | Degradation of proteins | | | Week 16 | End-of-term exam | | | |
| 1 | Creighton, T.E. 1993, PROTEINS Structures and Molecular Properties, W.H. Freeman and Company, New York | | | |
| 1 | Branden, C., Tooze, J., 1999, Introduction to Protein Structure, Garland Publishing Inc., New York. | | | 2 | Cox, M.M., Nelson, D.L., 2004, Lehninger Principles of Biochemistry, W.H. Freeman, New York | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 21/04/2022 | 1 | 30 | | Presentation | 12 | 12/05/2022 | 1 | 20 | | End-of-term exam | 16 | 14/06/2022 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Arasınav için hazırlık | 24 | 1 | 24 | | Arasınav | 1 | 1 | 1 | | Ödev | 11.5 | 2 | 23 | | Dönem sonu sınavı için hazırlık | 30 | 2 | 60 | | Dönem sonu sınavı | 1 | 1 | 1 | | Diğer 1 | 32 | 1 | 32 | | Total work load | | | 225 |
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