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| BIY7230 | Plant Secondary Metabolism | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Faik Ahmet AYAZ | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To explain metabolism of secondary plant products and their roles in plant system. Human health and plant secondary metabolism. Roles of secondary meabolites in interactions of organisms in ecosystem. Bioavailability of secondary metabolites. Production of plant secondary metabolites in biotechnology. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | describe the synthesis of plant secondary products
| 1,2,3 | 1,3, | | PO - 2 : | know role of these metabolites and their interactions between plant systems and the environment
| 1,2,3 | 1,3, | | PO - 3 : | classify plant secondary metabolism | 1,2,3 | 1,3, | | PO - 4 : | give a shortcut of the benefits and usage of these
compounds in alternative medicine and treatment | 1,2,3 | 1,5, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Introduction to plant secondary metabolites. Terpenoids. Synthesis of IPP. Prenyltransferase and terpene synthase reactions. Modification of terpenoid skeletons. Toward transgenic terpenoid production. Alkaloids. Alkaloid biosynthesis. Biotechnological application of alkaloid biosythesis researh. Phenylpropanoid and phenylpropanoid-acetate pathway metabolites. Phenylpropanoid and phenylpropanoid-acetate biosynthesis. Biosynthesis of lignans, lignins and suberization. Flavonoids. Coumarins, Stilbenes, styrylpyrones, and arylpyrones. Metabolic engineering of phenylpropanoid production |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Introduction to plant secondary metabolites. Terpenoids. | | | Week 2 | Synthesis of IPP. | | | Week 3 | Prenyltransferase and terpene synthase reactions. | | | Week 4 | Modification of terpenoid skeletons. | | | Week 5 | Toward transgenic terpenoid production. | | | Week 6 | Alkaoids and Alkaloids biosynthesis. | | | Week 7 | Biotechnological application of alkaloid biosythesis researh. | | | Week 8 | Phenylpropanoid and phenylpropanoid-acetate pathway metabolites.Phenols and phenolic acids | | | Week 9 | Mid-term exam | | | Week 10 | Biosynthesis of lignans, lignins and suberization. | | | Week 11 | Flavonoids | | | Week 12 | II. Exam | | | Week 13 | Anthocyanins. Coumarins, Stilbenes, styrylpyrones, and arylpyrones. | | | Week 14 | Carotens | | | Week 15 | Metabolic engineering of phenylpropanoid production | | | Week 16 | End-of-term exam | | | |
| 1 | Wink, M. 1999; Biochemistry of plant Secondary metabolism, Sheffield Academic Press, England | | | 2 | Heldt, H.-W. 2005.Plant Biochemitry, Elsevier Academic Press, London | | | |
| 1 | Taiz, L., Zeiger E. 2008: Plant Physiology, 3rd Ed., Sinauer Associates, Inc., Publishers, Massachusetts, USA
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| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 22/11/2021 | 1 | 30 | | Presentation | 12 | 10/12/2021 | 0,7 | 10 | | Homework/Assignment/Term-paper | 4
6 | 24/12/2021 | 10 | 10 | | End-of-term exam | 16 | 10/01/2022 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 4 | 14 | 56 | | Sınıf dışı çalışma | 4 | 14 | 56 | | Arasınav için hazırlık | 9 | 1 | 9 | | Arasınav | 1 | 1 | 1 | | Ödev | 5 | 4 | 20 | | Dönem sonu sınavı için hazırlık | 25 | 2 | 50 | | Dönem sonu sınavı | 1 | 1 | 1 | | Diğer 1 | 16 | 2 | 32 | | Total work load | | | 225 |
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