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| BIYI7132 | Molecular Virology | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Zihni DEMİRBAĞ | | Co-Lecturer | Asst. Prof. Dr. Remziye Nalçacıoğlu | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | | The main objectives of this course are to understand genome and gene expression of different viruses, to examine molecular mechanisms of viruses identified by practicing the molecular virology techniques in virology and to be aware of using viruses in genetic engineering and biotechnology |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Have knowledge about genome, genome replication and gene expression of different group of viruses in detail | 3,5,6,7 | 1 | | PO - 2 : | Do detail literature research on a specific virus including its significance in human life and in modern science | 3,5,6,7 | 3, 5, 6 | | PO - 3 : | Participate in discussion on viruses with his/her classmates | 3,5,6,7 | 5 | | PO - 4 : | Have detail information about host virus interactions | 3,5,6,7 | 1 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| History and development of virology and general concepts. Virus structure. Isolation growth and assay. Molecular biology of viruses. Bacteriophages. Human and animal virology. Retroviruses and AIDS. Viruses and cancer. Gene cloning in eukaryotic cells. Medical and applied virology. Plant viruses. Insect viruses. Biologic control, and gene expression and gene therapy |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | History and development of virology
| | | Week 2 | General concepts of virology
| | | Week 3 | Virus structure
| | | Week 4 | Isolation growth and assay
| | | Week 5 | Molecular biology of viruses. Bacteriophages
| | | Week 6 | Retroviruses and AIDS
| | | Week 7 | Viruses and cancer
| | | Week 8 | Gene cloning in eukaryotic cells
| | | Week 9 | Mid-term exam
| | | Week 10 | Medical and applied virology
| | | Week 11 | Current topics in molecular virology I | | | Week 12 | Current topics in molecular virology II | | | Week 13 | Plant viruses
| | | Week 14 | Insect viruses
| | | Week 15 | Biologic control, and gene expression and gene therapy
| | | Week 16 | End-of-term exam | | | |
| 1 | Cann, Alan J. 2001. Principles of Molecular Virology. Elsevier. Oxford, UK | | | |
| 1 | Flint, S.J. et al. 2000. Principles of Virology. ASM Press. USA | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 24/11/2021 | 1 | 30 | | Presentation | 12 | 16/12/2021 | 1 | 20 | | End-of-term exam | 16 | 21/01/2022 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 15 | 45 | | Sınıf dışı çalışma | 6 | 15 | 90 | | Laboratuar çalışması | 0 | 0 | 0 | | Arasınav için hazırlık | 2 | 8 | 16 | | Arasınav | 1 | 1 | 1 | | Uygulama | 0 | 0 | 0 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 2 | 10 | 20 | | Proje | 0 | 0 | 0 | | Kısa sınav | 0 | 0 | 0 | | Dönem sonu sınavı için hazırlık | 3 | 16 | 48 | | Dönem sonu sınavı | 0 | 1 | 0 | | Diğer 1 | 5 | 1 | 5 | | Diğer 2 | 0 | 0 | 0 | | Total work load | | | 225 |
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