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| KIML7781 | Active Methylene CompoundsandTheir Reactions | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of CHEMISTRY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | Assoc. Prof. Hacer BAYRAK | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The description of active methylene compounds, properties, synthesis reactions and reactions of methylene compounds and understanding their reaction mechanism. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Students will learn the structure and properties of methylene compounds and will learn the methods of obtaining and synthesis reactions. | | | | PO - 2 : | Students will learn some synthesis reactions of methylene compounds. | | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Active methylene compounds and Their Synthesis, synthesis reactions of methylene compound, reaction of ß-keto ester compounds, Thorpe reaction, The Thorpe-Ziegler reaction, Gewald reaction, Peterson reaction, Stobbe condensation reaction, Darzens reaction. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | The description of methylene compounds, properties and their synthesis reactions | | | Week 2 | The synthesis reaction of the methylene compounds | | | Week 3 | Reactions of ß-ketoester compounds and their reaction mechanisms | | | Week 4 | Reactions of ß-ketoester compounds and their reaction mechanisms | | | Week 5 | Thorpe reaction and the reaction mechanism | | | Week 6 | Discussing some literature examples of Thorpe reaction | | | Week 7 | Thorpe-Ziegler reaction and the reaction mechanism | | | Week 8 | Discussing some literature examples of Thorpe-Ziegler reaction | | | Week 9 | Mid-term exam | | | Week 10 | Gewald Reaction and the reaction mechanism | | | Week 11 | Discussing some literature examples of Gewald reaction | | | Week 12 | Peterson Reaction and the reaction mechanism | | | Week 13 | Discussing some literature examples of Peterson reaction | | | Week 14 | Stobbe condensation reaction, reaction mechanism and discussing some examples form literature | | | Week 15 | Darzens condensation reaction, reaction mechanism and discussing some examples form literature | | | Week 16 | End-of-term exam | | | |
| 1 | Li, J. J.; 2009, Name reactions: a collection of detailed reaction mechanisms, Springer | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 16/11/2016 | 1 | 50 | | End-of-term exam | 16 | 04/01/2017 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 5 | 14 | 70 | | Laboratuar çalışması | 0 | 0 | 0 | | Arasınav için hazırlık | 4 | 7 | 28 | | Arasınav | 2 | 1 | 2 | | Uygulama | 0 | 0 | 0 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 0 | 0 | 0 | | Proje | 0 | 0 | 0 | | Kısa sınav | 1 | 9 | 9 | | Dönem sonu sınavı için hazırlık | 3 | 10 | 30 | | Dönem sonu sınavı | 2 | 1 | 2 | | Diğer 1 | 0 | 0 | 0 | | Diğer 2 | 0 | 0 | 0 | | Total work load | | | 183 |
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