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| KIMI7316 | Carbohydrate Biochemistry and Related Research Techiques | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of CHEMISTRY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Murat KÜÇÜK | | Co-Lecturer | None | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | | Teaching structures, functions, and related techniques for structurally different carbohydrates and how some polysaccharides are used as research tools. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | learn the terminology about carbohydrates. | 1,3 | 1,3,5,6 | | PO - 2 : | learn the structures of carbohydrates. | 1,3 | 1,3,5,6 | | PO - 3 : | learn the functions of carbohydrates. | 1,3 | 1,3,5,6 | | PO - 4 : | learn how carbohydrate analyses are done. | 1,3 | 1,3,5,6 | | PO - 5 : | have knowledge of the importance of carbohydrate analyses in clinics and industry. | 1,3 | 1,3,5,6 | | PO - 6 : | learn the types of investigations carbohydrates can be used. | 1,3 | 1,3,5,6 | | PO - 7 : | learn how to develop a new method. | 1,3 | 1,3,5,6 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Carbohydrate structure, polysaccharides, chemical properties of carbohydrates, functions of carbohydrates, carbohydrates in molecular recognition, instrumental methods used in research, spectrometric methods used in research, conjugated carbohydrate structures, glycosidic bonds, classification of glycosides, quantity and structure analyses, use of carbohydrates and conjugates in analytical separations, examples from current literature. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Carbohydrate structure, disaccharides, oligosaccharides, polysaccharides | | | Week 2 | Chemical properties and interactions of carbohydrates | | | Week 3 | Metabolic pathways of carbohydrates and their regulation | | | Week 4 | Relationship of carbohydrate metabolism with other biochemical processes | | | Week 5 | Functions of carbohydrates (structural, energy source, etc.) | | | Week 6 | Transport of carbohydrates through membranes | | | Week 7 | Carbohydrates in molecular recognition | | | Week 8 | Carbohydrate test methods, spectrometric and other instrumental methods used in research | | | Week 9 | Mid-term exam | | | Week 10 | Conjugated carbohydrate structures, glycosidic bonds (with other carbohydrates, proteins, nucleic acids, flavonoids, tepenes, etc.) | | | Week 11 | Classification of glycosides, bioactive glycosides | | | Week 12 | Quantity and structure analyses | | | Week 13 | Isolation of carbohydrates (monomeric, oligomerc, polymeric carbohydrates) | | | Week 14 | Use of carbohydrates and conjugates in analytical separations | | | Week 15 | Timely examples about literature on the methods used in carbohydrate biochemistry | | | Week 16 | End-of-term exam | | | |
| 1 | D. L. Nelson and M. M. Cox, W. H., 2002; Lehninger Principles of Biochemistry, 4th edition, Freeman and Company. | | | |
| 1 | Voet and J.D. Voet, 1995; Biochemistry, 2nd edition, John Wiley and Sons Inc. | | | 2 | L. Stryer, M. B. Jeremy, J.L. Tymoczko, 2002; Biochemistry, 5th edition, W. H. Freeman and Company. | | | 3 | P.C. Champe, R.A. Harvey, 1994; Lippincott's Illustrated Reviews: Biochemistry, Champe, Lippincott Williams and Wilkins. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 20/11/2013 | 1,5 | 30 | | In-term studies (second mid-term exam) | 10 | 27.11.2013 | 1,5 | 20 | | End-of-term exam | 16 | 07/01/2014 | 1,5 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Sınıf dışı çalışma | 7 | 14 | 98 | | Arasınav için hazırlık | 10 | 1 | 10 | | Ödev | 2 | 7 | 14 | | Total work load | | | 122 |
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