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| EBK6008 | Mechanisms of Act.Of Anti.Drugs | 4+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of BIOCHEMISTRY (PHARMACY) | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face, Group study | | Contact Hours | 14 weeks - 4 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | | The aim of mechanisms of action of antiviral drugs for graduate program students is to introduce antiviral drugs and their action mechanisms that will be beneficial throughout their educational and professional life. During this course the basic virology and mechanisms of action of antiviral drugs will be taught to students. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | The general structure of viruses are learned. | 1,2,3,4,5,6,7,8,9,10,11 | | | PO - 2 : | Replication strategies of viruses are learned. | 1,2,3,4,5,6,7,8,9,10,11 | | | PO - 3 : | Targets of antivral drugs and mechanism of their action are learned. | 1,2,3,4,5,6,7,8,9,10,11 | | | PO - 4 : | Antiviral resistance mechanisms are learned. | 1,2,3,4,5,6,7,8,9,10,11 | | | PO - 5 : | Infection control is learned. | 1,2,3,4,5,6,7,8,9,10,11 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Mechanisms of action of antiviral drugs course include lectures and presentations.
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Structure of viruses and their properties | | | Week 2 | Replication of viruses | | | Week 3 | Mechanism of viral infection and virus dissemination | | | Week 4 | Viral Pathogenesis | | | Week 5 | Antiviral drugs and selective toxicity | | | Week 6 | Targets for antiviral drugs and mechanism of their action | | | Week 7 | Mid-term Exam | | | Week 8 | Attachment, penetration and uncoating inhibitors | | | Week 9 | Nucleic acid inhibitors | | | Week 10 | Reverse transcriptase (RT) inhibitors | | | Week 11 | Nucleoside analogues (RT) inhibitors | | | Week 12 | RNA polymerase inhibitors | | | Week 13 | Protein synthesis inhibitors | | | Week 14 | Olgunlaşma ve salınım inhibitörleri | | | Week 15 | Antiviral drug resistance | | | Week 16 | Final Exam | | | |
| 1 | Patrick R. Murray, Ken S. Rosenthal and Michael A. Pfaller Medical Microbiology 7th EditionELSEVIER2013ISBN-9781437715286 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 15 | 10.04.2019 | 1 | 50 | | End-of-term exam | 21 | 23.05.2019 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 4 | 14 | 56 | | Sınıf dışı çalışma | 4 | 4 | 16 | | Arasınav için hazırlık | 4 | 2 | 8 | | Arasınav | 4 | 1 | 4 | | Ödev | 4 | 4 | 16 | | Dönem sonu sınavı için hazırlık | 4 | 2 | 8 | | Dönem sonu sınavı | 4 | 1 | 4 | | Total work load | | | 112 |
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