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| EBK6006 | Vaccine Development Strategies | 4+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of BIOCHEMISTRY (PHARMACY) | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 4 hours of lectures per week | | Lecturer | Prof. Dr. Atila Taner KALAYCIOĞLU | | Co-Lecturer | | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | | The aim of vaccine development strategies for graduate program students is to introduce vaccines and vaccine development strategies that will be beneficial throughout their educational and professional life. During this course the basic immunology, the working mechanism of the immune system and vaccine development strategies will be taught to students. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Operation principles of immune system are learned. | 1,2,3,4,5,6,7,8,9,10,11 | 1,3 | | PO - 2 : | Knowledge of antigens and immunogens will be gained. | 1,2,3,4,5,6,7,8,9,10,11 | 1,3 | | PO - 3 : | Antigen preparations used in vaccines are learned. | 1,2,3,4,5,6,7,8,9,10,11 | 1,3 | | PO - 4 : | Live and killed vaccines and their immune response elicited in individulas are learned. | 1,2,3,4,5,6,7,8,9,10,11 | 1,3 | | PO - 5 : | New generation of vaccine development strategies are learned. | 1,2,3,4,5,6,7,8,9,10,11 | 1,3 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Vaccine development strategies course include lectures and presentations.
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Introduction to the Immune System (Nomenclature, General Properties, and Components) | | | Week 2 | Innate and Adaptive Immunity | | | Week 3 | Vaccines and antigens | | | Week 4 | Live-attenuated and killed vaccines
| | | Week 5 | Inactivated toxin and toxoid bacterial vaccines | | | Week 6 | Non-replicating virüs vaccines | | | Week 7 | Recombinant DNA technology and vaccines | | | Week 8 | Mid-term exam | | | Week 9 | Reverse vaccinology approach | | | Week 10 | Virus-like particles | | | Week 11 | Improving immunogenicity through formulation | | | Week 12 | Improving immunogenicity by including immune modulatory adjuvants | | | Week 13 | Improving immunogenicity by using next generation delivery systems | | | Week 14 | Viral vectors | | | Week 15 | Factors affecting vaccine efficacy and safety | | | Week 16 | End-of-term exam | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 15 | 10.04.2019 | 1 saat | 50 | | End-of-term exam | 21 | 23.05.2019 | 1 saat | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 4 | 14 | 56 | | Arasınav için hazırlık | 4 | 1 | 4 | | Arasınav | 4 | 1 | 4 | | Ödev | 4 | 2 | 8 | | Dönem sonu sınavı için hazırlık | 4 | 1 | 4 | | Dönem sonu sınavı | 4 | 1 | 4 | | Total work load | | | 80 |
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