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| EFG5101 | Biosynthesis of Natural Compounds | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACOGNOSY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Gülin RENDA | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The aim of this course is focused on the biosynthesis of natural substances, biosynthetic pathways, primary and secondary metabolites, isoprenoids, aromatics, shikimates, polyphenols and the biosynthesis of alkaline substances. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Will be able to relate primary and secondary metabolites with biosynthesis of natural products. | 2 | 1, | | PO - 2 : | Will be able to classify important natural products produced by biosnythetic pathways. | 2 | | | PO - 3 : | Can discuss the importance and usage of biosynthetic secondary metabolites in pharmacy. | 2 | | | PO - 4 : | Can explain biochemical processes in biological systems. | 2 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| This course includes basic metabolic processes, biosynthetic pathways in plants, biosynthesis of natural substances, biosynthesis associated with pharmacognosy and secondary metabolites used in pharmacy. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Primary and secondary metabolism | | | Week 2 | Biosynthetic pathways in plants | | | Week 3 | Biosynthesis of isoprenoids and significance | | | Week 4 | Biosynthesis of isoprenoids and significance | | | Week 5 | Biosynthesis of aromatic compounds | | | Week 7 | Secondary metabolites of shikimate pathway | | | Week 8 | Mid-term exam | | | Week 9 | Organic acids, phenyl propanoids, chinons and coumarines | | | Week 10 | Polyphenols, lignins and lignans | | | Week 11 | Biosynthesis of alkaloids | | | Week 12 | Nitrogen assimilation and amino acids | | | Week 13 | Phenyl alanine, tyrosine, lysine derivatives | | | Week 14 | Ornithine, trypthamine, adenine, guanine and xanthine derivatives | | | Week 15 | Natural product secondary metabolites used in pharmacy | | | Week 16 | End-of-term exam | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | 18/11/2021 | 1,00 | 30 | | Presentation | 14 | 03/01/2021 | 2 | 20 | | End-of-term exam | 14 | 06/01/2021 | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 2 | 10 | 20 | | Laboratuar çalışması | 0 | 0 | 0 | | Arasınav için hazırlık | 4 | 4 | 16 | | Arasınav | 1 | 1 | 1 | | Uygulama | 0 | 0 | 0 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 2 | 2 | 4 | | Proje | 0 | 0 | 0 | | Kısa sınav | 0 | 0 | 0 | | Dönem sonu sınavı için hazırlık | 4 | 10 | 40 | | Dönem sonu sınavı | 1 | 1 | 1 | | Diğer 1 | 0 | 0 | 0 | | Diğer 2 | 0 | 0 | 0 | | Total work load | | | 124 |
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