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| EAK5012 | Prac. Electroanalytical Methods in Drug Analysis | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | ANALYTICAL CHEMISTRY IN PHARMACY | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The aim of this course is to teach how to practically analyse pure drugs and pharmaceutical active ingredients in pharmaceuticals and biological samples (blood and urine exc.) using electroanalytical methods. Thus, students will effectively use these methods used in the industry and scientific laboratories. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Have information on recent electroanalytical methods commonly used. | 4,10 | 1,3, | | PO - 2 : | Have information on the applications of the electroanalytical methods. | 4,10 | 1,3, | | PO - 3 : | Learn how to use the methods learned theoretically in practice. | 4,10 | 1,3, | | PO - 4 : | Can apply electroanalytical methods in the laboratory. | 4,10 | 1,3, | | PO - 5 : | Learn how to interpret the results obtained experimentally using electroanalytical methods. | 4,10 | 1,3, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| It includes recent applications of the electroanalytical methods used for the analysis of drugs. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | General definition of the electroanalytical methods used in drug analysis | | | Week 2 | Electric charge, chemical charge and charge transfer in electrolysis cells, electrolysis stoichiometric relationship | | | Week 3 | Electrolysis reactions in aqueous solutions, definition of working electrodes, definition of reference electrodes, measurements of the cell potential and pH | | | Week 4 | Experimental potentiometric measurements and potentiometric titrations | | | Week 5 | Measurement methods based on electrical conductivity | | | Week 6 | Conductometry, conductometric and amperometric titrations | | | Week 7 | Voltametric methods: Linear sweep voltammetry, cyclic voltammetry, and pulse voltammetry techniques | | | Week 8 | Polarography and its applications | | | Week 9 | Mid-term exam | | | Week 10 | Usage of electroanalytical methods from the example data | | | Week 11 | Evaluation of the experimental results obtained from the electroanalytical methods | | | Week 12 | Evaluation of the experimental results obtained from the electroanalytical methods | | | Week 13 | Study of the electroanalytical method applications on the examples in the literature | | | Week 14 | Study of the electroanalytical method applications on the examples in the literature | | | Week 15 | Summarize of the electroanalytical method applications | | | Week 16 | End-of-term exam | | | |
| 1 | Ermer, J., McB Miller, J.H. 2005; Method Validation in Pharmaceutical Analysis: A Guide to Best Practice, Wiley-VCH. | | | 2 | Wang, J. 2006; Analytical Electrochemistry, 3. Baskı, Wiley-VCH. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 15/04/2024 | 2 | 30 | | In-term studies (second mid-term exam) | 15 | 01/06/2024 | 2 | 20 | | End-of-term exam | 16 | 03/06/2024 | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Arasınav için hazırlık | 3 | 8 | 24 | | Arasınav | 2 | 1 | 2 | | Dönem sonu sınavı için hazırlık | 8 | 15 | 120 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 190 |
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