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| BIY4031 | @Enzymology | 3+0+0 | ECTS:5 | | Year / Semester | Fall Semester | | Level of Course | First Cycle | | Status | Elective | | Department | DEPARTMENT of BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Dr. Öğr. Üyesi Fulya AY | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To learn basic information and methods about enzymology. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | They will have knowledge about the structure, kinetics and catalysis mechanisms of enzymes. | | | | LO - 2 : | They will learn about enzymes used in biotechnological applications. | | | | LO - 3 : | They will have knowledge about purification and immobilization techniques of enzymes. | | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| Overview of enzymology, general properties of enzymes, classification of enzymes, enzyme catalysis mechanisms, enzyme kinetics, enzymes used in industrial fields - fermenter systems, enzyme isolation and purification methods. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Overview of enzymology, general properties of enzymes | | | Week 2 | General properties of enzymes | | | Week 3 | Classification of enzymes | | | Week 4 | Enzyme catalysis mechanisms | | | Week 5 | Enzyme kinetics | | | Week 6 | Enzyme inhibitions | | | Week 7 | Enzyme activity detection methods | | | Week 8 | Enzyme activity, cofactors and factors affecting enzyme activity | | | Week 9 | Midterm exam | | | Week 10 | Student seminars | | | Week 11 | Student seminars | | | Week 12 | Student seminars | | | Week 13 | Enzyme isolation and purification methods | | | Week 14 | Enzyme immobilization | | | Week 15 | Enzymes-fermenter systems used in industrial areas | | | Week 16 | Final exam | | | |
| 1 | Figen Gürdöl, Evin Ademoğlu, 2010., Biyokimya, Nobel Tıp Yayınları, İstanbul | | | 2 | Edip Keha, İrfan Küfrevioğlu, Biyokimya, 2012., Aktif yayınevi, Erzurum. | | | 3 | Lehninger, Biyokimyanın ilkeleri, 2021. Palme yayınevi, Ankara. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 15/04/2024 | 60 | 30 | | Presentation | 11 | 29/04/2024 | 30 | 20 | | End-of-term exam | 16 | 03/06/2024 | 60 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Laboratuar çalışması | 0 | 0 | 0 | | Arasınav için hazırlık | 2 | 7 | 14 | | Arasınav | 2 | 1 | 2 | | Uygulama | 0 | 0 | 0 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 3 | 1 | 3 | | Proje | 0 | 0 | 0 | | Kısa sınav | 0 | 0 | 0 | | Dönem sonu sınavı için hazırlık | 5 | 5 | 25 | | Dönem sonu sınavı | 3 | 1 | 3 | | Diğer 1 | 3 | 5 | 15 | | Diğer 2 | 2 | 2 | 4 | | Total work load | | | 150 |
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