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| BIY3004 | Radiobiology | 3+0+0 | ECTS:6 | | Year / Semester | Spring Semester | | Level of Course | First Cycle | | Status | Elective | | Department | DEPARTMENT of BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face, Group study | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Kamil ÇOŞKUNÇELEBİ | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | This course is designed to present an introduction to the general concept of Radiobiology. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Describe and explain EMR and PR
| 1,5,7 | 1,5, | | LO - 2 : | Explain the effect of EMR and PR on human cells, tissue and organs | 1,5,7 | 1,5, | | LO - 3 : | Summaries the importance and dangerous of Radiation on Human body | 1,5,7 | 1,5, | | LO - 4 : | Summaries the types of Radiations | 1,5,7 | 1,5, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| History of radiobiology, radiobiological terms and concepts, radiation and the effect mechanism of radiation, radiation types, absorption of radiation, radicals, radiation units, detectors, effects of radiation on bio-macromolecules, cells, tissues, organs and organism (especially human) . Detection of radiation level and types of protection from several kind of radiation. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Basic term and its explanations
| | | Week 2 | Ionization Radiation
| | | Week 3 | Linear energy tranfery (LET) and Relative Biological Effect (RBE) | | | Week 4 | Effect of IR on nucleic acids | | | Week 5 | Effects of IR on subcellular level
| | | Week 6 | Kinetics of cell populations | | | Week 7 | Effect of IR on cell growth
| | | Week 8 | Negative effects caused by IR in the cell and its restoration process in the cell | | | Week 9 | Mid-term exam | | | Week 10 | Radicals
| | | Week 11 | The effect of IR on cell cyclus
| | | Week 12 | Radiosensitivors | | | Week 13 | Radioprotectors
| | | Week 14 | Effects of IR on tissue and organs | | | Week 15 | The late effect of IR: genetic and carsinogen effects of IR
| | | Week 16 | End-of-term exam | | | |
| 1 | Temel Radyobiyoloji, Haliç Üniversitesi Yayınları, İstanbul, Atila Özalpan, 2002. | | | |
| 1 | Introduction to Radiaobiology. Willey and Sons Ltd., London, 2000. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 24/04/2023 | 1 | 35 | | Homework/Assignment/Term-paper | Seminer | 02,09/06/2023 | | 15 | | End-of-term exam | 16 | 13/06/2023 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 2.5 | 14 | 35 | | Arasınav için hazırlık | 2.5 | 8 | 20 | | Arasınav | 1.5 | 5 | 7.5 | | Ödev | 1 | 14 | 14 | | Dönem sonu sınavı için hazırlık | 2 | 10 | 20 | | Dönem sonu sınavı | 1.5 | 1 | 1.5 | | Diğer 1 | 2 | 20 | 40 | | Total work load | | | 180 |
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