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| BIY4037 | Molecular Biology | 3+0+0 | ECTS:6 | | Year / Semester | Fall Semester | | Level of Course | First Cycle | | Status | Compulsory | | Department | DEPARTMENT of BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Ali Osman BELDÜZ | | Co-Lecturer | Prof. Dr. Ali Osman BELDUZ | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | This course tries to give a solid understanding of the nature and organisation of the genetic material, and the mechanisms of replication, transmission and change, and the processes controlling its expression. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | describe the structure of nucleic acids | 1,3,7 | 1, | | LO - 2 : | explain gene organisation and expression | 1,3,7 | 1, | | LO - 3 : | explain mutations, repair and replication of DNA | 1,3,7 | 1, | | LO - 4 : | describe techniques of the isolation and safely manipulation of nucleic acids in the laboratory | 1,3,7 | 1, | | LO - 5 : | explain principles of analyses methods of nucleic acids | 1,3,7 | 1, | | LO - 6 : | explain basic nucleic acid manipulations | 1,3,7 | 1, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| System and methods of molecular biology, macromolecules, DNA technology, DNA replication, repair, mutation, transcription and translation, gene regulation, genetic engineering, oncogenes and cancer. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | System and Methods of Molecular Biology
| | | Week 2 | Genetic Analysis in Molecular Biology
| | | Week 3 | Macromolecules
| | | Week 4 | Structure of Nucleic Acids
| | | Week 5 | Fundamentals of basic recombinant DNA techniques
| | | Week 6 | DNA Replication
| | | Week 7 | DNA Replication | | | Week 8 | Repair | | | Week 9 | Mid-term exam | | | Week 10 | Mutagenesis
| | | Week 11 | Mutations and Mutants
| | | Week 12 | Transcription
| | | Week 13 | Translation
| | | Week 14 | Translation
| | | Week 15 | The Machinary and the Chemical Nature of Chemical Synthesis
| | | Week 16 | End-of-term exam | | | |
| 1 | Books, CDs and Slayts are available. | | | 2 | Molecular Biology, Lecture Notes, 2008, Trabzon | | | |
| 1 | Watson, James. Molecular Biology of the Gene. 5th ed. San Francisco, CA: Pearson /Benjamin Cummings, 2003. For Laboratory Safety; http://userpages.umbc.edu/~jwolf/method2a.htm | | | 2 | Molecular Biology, David Freifelder. Jones and Bartlett Publishers Inc. Boston, USA, 1985. Molecular Biology, Second Edition, Robert F. Weaver, Mc Graw-Hill, 859 p. , 2003. | | | 3 | Instant Notes in Molecular Biology. P. C. Turner, A. G. McLennan, A. D. Bates, and M. R. H. White, Bios Scientific Publishers, UK. , 1997. | | | 4 | A.Yıldırım, F. Bardakçı, M. Karataş, B. Tanyolaç. (eds), Moleküler Biyoloji. Nobel Yayın Dağıtım, Ankara, (2007). ISBN 978-9944-77-184-9. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 22/11/2021 | 90 | 50 | | End-of-term exam | 16 | 12/01/2022 | 90 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Laboratuar çalışması | 0 | 0 | 0 | | Arasınav için hazırlık | 5 | 7 | 35 | | Arasınav | 2 | 4 | 8 | | Uygulama | 0 | 0 | 0 | | Klinik Uygulama | 0 | 0 | 0 | | Ödev | 0 | 0 | 0 | | Proje | 0 | 0 | 0 | | Kısa sınav | 0 | 0 | 0 | | Dönem sonu sınavı için hazırlık | 5 | 10 | 50 | | Dönem sonu sınavı | 2 | 1 | 2 | | Diğer 1 | 1 | 1 | 1 | | Diğer 2 | 0 | 0 | 0 | | Total work load | | | 180 |
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