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| KIM7310 | Acid-Base & Ionic Balance in Biological Media | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Third Cycle | | Status | Elective | | Department | DEPARTMENT of CHEMISTRY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | None | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | | Discussion of the events and terms related to the formation and maintenance of acid ? base and ionic balance in biological media at graduate level, making thebiochemical processes better understood, and thus contributing to the correct use of buffer and ion compositions during biochemical investigations and tests. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Learn the terminology in acid-base and ionic balance. | 1,2,3 | 1,3,5,6 | | PO - 2 : | learn equilibrium and dynamic steady state concepts. | 1,2,3 | 1,3,5,6 | | PO - 3 : | learn properties and preparations of buffer solutions. | 1,2,3 | 1,3,5,6 | | PO - 4 : | learn acid-base and ionic balances important for biological systems. | 1,2,3 | 1,3,5,6 | | PO - 5 : | learn the tissue and organs important for acid-base and ionic balance and their roles. | 1,2,3 | 1,3,5,6 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Acidity and basicity, buffering, Henderson-Hasselbalch equation and applications, acidity and basicity of biological structures, buffering in biological systems, acidosis and alkalosis, macro and micro elements playing role in ionic balance of biological systems and their distribution, ionic strength, contribution of biomacromolecules to acid-base and ionic balance, important organs that play significant roles in acid-base and ionic balance of the organism and their functions. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Solutions, preparing solutions | | | Week 2 | Acidity and basicity | | | Week 3 | Weak acids and bases | | | Week 4 | Buffering, titration graphs of weak acids | | | Week 5 | Henderson-Hasselbalch equation and its applications | | | Week 6 | Acidity and basicity of biological molecules | | | Week 7 | Buffering in biological systems | | | Week 8 | Mid-term exam | | | Week 9 | Acidosis and alkalozis | | | Week 10 | Micro and macro elements playing role in ionic balance in biological systems and their distributions | | | Week 11 | Ionic strength and its effects on biomolecules | | | Week 12 | The contribution of biomacromolecules on acid-base and ioic balance | | | Week 13 | Tissues and organs having important roles in acid-base and ionic balance in organisms and their functions, Project | | | Week 14 | Timely examples about literature on acid-base balance and presentations | | | Week 15 | Timely examples about literature on ionic balance and presentations | | | Week 16 | End-of-term exam | | | |
| 1 | D.L. Nelson and M. M. Cox, W. H., 2002; Lehninger Principles of Biochemistry, 4th edition, Freeman and Company, ABD. | | | |
| 1 | Voet and J.D. Voet, 2005; Biochemistry, 4th edition, John Wiley and Sons Inc., ABD. | | | 2 | L. Stryer, M. B. Jeremy, J.L. Tymoczko, 2002; Biochemistry, 5th edition, W. H. Freeman and Company, ABD. | | | 3 | P.C. Champe, R.A. Harvey, Champe, 1994; Lippincott's Illustrated Reviews: Biochemistry, Lippincott Williams and Wilkins, ABD. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | 29/03/2010 | 1,5 | 30 | | Project | 13 | 05/05/2010 | 2 | 10 | | Presentation | 14
15 | 12/05/2010
19/05/2010 | 1
1 | 5 | | End-of-term exam | 16 | 27/05/2010 | 1,5 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 7 | 14 | 98 | | Arasınav için hazırlık | 10 | 1 | 10 | | Arasınav | 2 | 1 | 2 | | Ödev | 2 | 7 | 14 | | Proje | 20 | 1 | 20 | | Dönem sonu sınavı için hazırlık | 12 | 1 | 12 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 200 |
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