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| ECZ4032 | Pharmaceutical Chemistry Laboratory - IV | 0+0+3 | ECTS:2 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Compulsory | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of laboratory per week | | Lecturer | -- | | Co-Lecturer | Assist. Prof. Hasan Erdinç Sellitepe, Assist. Prof Sevda TÜRK, Res. Assist. Ahmet Buğra Aksel | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | *Lab.:Teaching techniques used in qualitative analysis of drugs and structure elucidation.
Evaluate the structure-activity relationships and chemical analyses and syntheses of drugs acting on gastrointestinal and endocrine systems and radiodiagnostic drugs. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Discuss basic principles of instrumental analysis methods. | 3,4,5,9 | 1,4,5, | | LO - 2 : | Distinguish the application fields of instrumental analysis methods. | 3,4,5,9 | 1,4,5, | | LO - 3 : | Compare advantages and disadvantages of the methods. | 3,4,5,9 | 1,4,5, | | LO - 4 : | Debate the structure-activity relationships and chemical analyses and syntheses of drugs acting on gastrointestinal system. | 3,4,5,9 | 1,4,5, | | LO - 5 : | Debate the structure-activity relationships and chemical analyses and syntheses of drugs acting on endocrine system. | 3,4,5,9 | 1,4,5, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| *Lab.:Instrumental techniques that are used for qualitative analysis of drugs.
Gastrointestinal and endocrine system drugs and radiodiagnostic drugs. antidiyabetikler, hormonlar, tiroit hormonlar, peptit hormonlar, streoit hormonlar, Dijestan ve karminatifler, antiemetik ilaçlar, antiasitler ve ülser tedavisinde kullanılan ilaçlar, laksatif-purgatifler, antidiyareikler, antiallerjik ilaçlar, vitaminler, diagnostik bileşikler . |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Digestive system drugs (introduciton, terms, coloretic, collagogs, digestives)
*Lab.:ORGANIC MATTER ANALYSIS, element assignment - demo | | | Week 2 | Digestive system drugs (Emetics and anti-emetics, hepatic drugs)
*Lab.:organic matter and element analysis experiment | | | Week 3 | Digestive system drugs (ulcer, gastrid)
*Lab.:organic matter and element analysis experiment | | | Week 4 | Digestive system drugs(Lacsatives and anti-diarrhea drugs)
*Lab.:organic matter and element analysis experiment | | | Week 5 | Digestive system drugs (diabet)
*Lab.:organic matter and element analysis experiment | | | Week 6 | Drugs affecting endocrine systeme, introduction and terms, hormones
*Lab.: Spectral methods-demo | | | Week 7 | Drugs affecting endocrine systeme,tiroit hormones, introduction to peptide hormones
*Lab.:Spectral methods-demo | | | Week 8 | Midterm exam | | | Week 9 | Drugs affecting endocrine systeme,peptide hormones
*Lab.:Spectral methods-demo | | | Week 10 | Drugs affecting endocrine systeme,stereoid hormonları
*Lab.:Spectrum solution | | | Week 11 | Drugs affecting endocrine systeme,stereoid hormones
*Lab.:Spectrum solution | | | Week 12 | Non-stereoidal antiinflamatory drugs
*Lab.:Spectrum solution | | | Week 13 | Analeptics, analgesic drugs
*Lab.:homework article presentation (article, drug synthesis, analysis, structure-activity) | | | Week 14 | Antitussive and expectorant drugs
*Lab.:homework article presentation (article, drug synthesis, analysis, structure-activity) | | | Week 15 | antiallergic and antihistaminic drugs
*Lab.:compensation | | | Week 16 | Final exam | | | |
| 1 | Akgün, H., Balkan, A., Bilgin, A.A., Çalış, Ü., Dalkara, S., Erdoğan, H., Erol Demir, D., Ertan, M.,Gökhan, N., Özkanlı, F., Palaska, E., Saraç, S. ve Şafak, C.,Tozkoparan.B. 2004; Farmasötik Kimya, Hacettepe Üniversitesi Yayınları, Ankara. | | | |
| 1 | Gündüz, T. 1999; İnstrumental Analiz, Gazi kitabevi, Ankara. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 14/11/2021 | 2 | 30 | | Laboratory exam | 9 | 14/11/2021 | 2 | 20 | | Presentation | 14 | 12.12.2021 | 3 | 10 | | End-of-term exam | 16 | 10.01.2022 | 2 | 40 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 13 | 39 | | Laboratuar çalışması | 3 | 13 | 39 | | Arasınav için hazırlık | 1 | 2 | 2 | | Arasınav | 1 | 1 | 1 | | Ödev | 2 | 1 | 2 | | Proje | 1 | 1 | 1 | | Dönem sonu sınavı için hazırlık | 1 | 1 | 1 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 87 |
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