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ECZ3034 | Pharmaceutical Technology Laboratory - II | 0+0+3 | ECTS:2 | Year / Semester | Spring Semester | Level of Course | Second Cycle | Status | Compulsory | Department | DEPARTMENT of PHARMACEUTICS | Prerequisites and co-requisites | None | Mode of Delivery | | Contact Hours | 14 weeks - 3 hours of laboratory per week | Lecturer | Dr. Öğr. Üyesi Seçkin ENGİN | Co-Lecturer | Seçkin ENGİN | Language of instruction | Turkish | Professional practise ( internship ) | None | | The aim of the course: |
It is aimed to learn the laboratory information necessary for the preparation and control of magistral drugs in suspension, emulsion and semi-solid dosage forms.
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Learning Outcomes | CTPO | TOA | Upon successful completion of the course, the students will be able to : | | | LO - 1 : | gain knowledge about the basic principles, basic measurements and calculations in drug preparation. | 1,2,5,9 | 1, | LO - 2 : | learns the preparation of magistral preparations. | 1,2,5,9 | 1, | LO - 3 : | learns the preparation of suspension and emulsion type drug dosage forms and sample preparations. | 1,2,5,9 | 1, | LO - 4 : | learns the preparation of semi-solid drug dosage forms and sample preparations. | 1,2,5,9 | 1, | LO - 5 : | learns the necessary controls for suspension and emulsion type drug dosage forms. | 1,2,5,9 | 1, | LO - 6 : | learns the necessary controls for semi-solid drug dosage forms. | 1,2,5,9 | 1, | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | |
It includes the preparation and controls of magistral drugs in suspension, emulsion and semi-solid dosage forms.
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Course Syllabus | Week | Subject | Related Notes / Files | Week 1 | Laboratory Information Lesson | | Week 2 | Modified Schamberg's Lotion
Kaolin Pectin Suspension | | Week 3 | Calculation of Sedimentation Volume in Suspensions | | Week 4 | Surface Effectiveness, Olive Oil Emulsion | | Week 5 |
Surface Effectiveness, Olive Oil Emulsion | | Week 6 | Viscosity Measurement Methods | | Week 7 | Liquid Paraffin Emulsion-Dry gum method,
Liquid Paraffin Emulsion-Wet glue method,
Lime Lime | | Week 8 | Simple Ointment
Hydrophilic Ointment
Glycerin Ointment | | Week 9 | Midterm exam | | Week 10 | Zinc Oxide Ointment ? ??Study 12
Zinc Oxide Paste
Zinc Oxide Gelatin
| | Week 11 | Rivanol Ointment
Wilkinson's Ointment
Coal Tar Ointment | | Week 12 | Examination of Some Properties of Different Ointment Plasters and Factors of the Ointments
Examination of Material Output | | Week 13 | Ichthyol Ovule
Soapy Glycerin Suppository | | Week 14 | Aspirin- Paracetamol Suppository
Chloralhydrate Suppository
In-Vitro Examination of Active Substance Release from Suppositories ? Study 23 | | Week 15 | Prescription practice | | Week 16 | Final Exam | | |
1 | Dermatological and Transdermal Formulations (Drugs and the Pharmaceutical Sciences), Kenneth A. Walters, Feb 20, 2002 | | 2 | Drug Permeation Enhancement (Drugs and the Pharmaceutical Sciences), Hsieh, Sep 17, 1993 | | 3 | Encyclopedia of pharmaceutical technology volume 1-5 | | 4 | Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods, Fourth Edition (Drugs and the Pharmaceutical Sciences), Robert L. Bronaugh, Howard I. Maibach, Jul 25, 2005 | | 5 | Surfactants and Polymers in Drug Delivery (Drugs and the Pharmaceutical Sciences) by Martin Malmsten (Hardcover - Jul 22, 2002 | | 6 | Topical Drug Delivery Formulations (Drugs and the Pharmaceutical Sciences), Osborne, Michael J. Rathbone, Michael S. Roberts, and Jonathan Hadgraft, Nov 7, 2002 | | |
1 | The Complete Drug Reference, 1992, United States Pharmacopeial Convention Inc. Permission granted, Consumer Reports Books | | |
Method of Assessment | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | Mid-term exam | 9 | Nisan 2024 | 2 | 38 | In-term studies (second mid-term exam) | 1 2 3 4 5 6 7 8 10 11 12 13 14 15 | | 3 | 6 | Quiz | 1 2 3 4 5 6 7 8 10 11 12 13 14 15 | | 0,15 | 6 | Laboratory exam | 16 | | 1 | 15 | End-of-term exam | 16 | Haziran 2024 | 2 | 35 | |
Student Work Load and its Distribution | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | Laboratuar çalışması | 3 | 14 | 42 | Arasınav | 2 | 1 | 2 | Uygulama | 3 | 1 | 3 | Dönem sonu sınavı | 2 | 1 | 2 | Total work load | | | 49 |
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