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| ECZ2002 | Biochemistry Fundamentals of Diseases | 2+0+0 | ECTS:4 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Prof. Dr. Sermet YILDIRMIŞ | | Co-Lecturer | SERMET YILDIRMIŞ | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | provide what the biochemical basis of metabolic diseases |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Understand the importance of examining the biochemical aspects of the disease | 1,2,8,10 | | | LO - 2 : | Describe the disease agent | 1,2,8,10 | | | LO - 3 : | Tell carbohydrate metabolism disorders | 1,2,8,10 | | | LO - 4 : | Tell lipid metabolism disorders | 1,2,8,10 | | | LO - 5 : | Tell protein metabolism disorders | 1,2,8,10 | | | LO - 6 : | Tell the biochemistry of hereditary diseases | 1,2,8,10 | | | LO - 7 : | Tell biochemical basis of hematological diseases | 1,2,8,10 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| Biochemistry of metabolic diseases, innovative approaches, biochemistry of hereditary diseases , the biochemical basis of hematological disorders , mitochondrial and pharmacogenetic disorders, transport disturbances, Biochemistry of neurodegenerative diseases , amyloid diseases ( Parkinson 's and Alzheimer's ) and biochemical basis , the biochemistry of psychiatric diseases , biochemistry, immunological diseases, cancer biochemistry, autoimmune diseases . |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | General information about metabolic diseases | | | Week 2 | Classification of metabolic diseases | | | Week 3 | Carbohydrate metabolism disorders | | | Week 4 | Lipid metabolism disorders | | | Week 5 | Protein metabolism disorders | | | Week 6 | biochemistry of metabolic diseases | | | Week 7 | Biochemistry of inherited diseases | | | Week 8 | Mitochondrial disorders and pharmacogenetics ,The biochemical basis of hematological disorders | | | Week 9 | Mitderm | | | Week 10 | transport disorders, biochemistry of neurodegenerative diseases | | | Week 11 | amyloid diseases (Parkinson 's and Alzheimer's ) and biochemical fundamentals | | | Week 12 | biochemistry of psychiatric disorders | | | Week 14 | Biochemistry of cancer , auto-immune diseases | | | Week 15 | Biochemistry of cancer , auto-immune diseases | | | Week 16 | Final exam | | | |
| 1 | Albert, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. Molecular Biology of the Cell, Garland Science, New York, 2002. | | | |
| 1 | Ohlendieck K. Biochemistry of Neuromuscular Diseases, Biochemistry and Molecular Biology Education, vol.30, pp. 372, 2002. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 17/04/2024 | 1 | 50 | | End-of-term exam | 16 | 06/06/2024 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 14 | 2 | 28 | | Arasınav için hazırlık | 1 | 8 | 8 | | Arasınav | 1 | 2 | 2 | | Ödev | 2 | 12 | 24 | | Kısa sınav | 1 | 2 | 2 | | Dönem sonu sınavı için hazırlık | 2 | 2 | 4 | | Dönem sonu sınavı | 1 | 2 | 2 | | Total work load | | | 70 |
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