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| ECZ3051 | Biochemistry of Cancer | 2+0+0 | ECTS:4 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Doç. Dr. Burak BARUT | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To have knowledge about the biochemistry, genetics, markers and treatment of cancer. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | May have information about the definition, mortality and morbidity of cancer.
May have information about tumor markers.
May have knowledge about the biochemistry, genetics, epigenetics and treatment of cancer. | 5,6,13 | 1, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| What is cancer? Cancer Morbidity and Mortality in the World and Turkey Main Differences of Cancer Cells from Healthy Cells Cell Death Mechanisms Cell Cycle Control and Cancer Cancer DNA Repair and DNA Repair Pathways in Treatment Tumor Suppressor Genes
Oncogenes Biochemical Methods in Cancer Diagnosis and Follow-up Discovery of New Biomarkers for Cancer Diagnosis and Treatment Design, Development and Discovery of Anti-Cancer Drugs Cancer treatment methods (Chemotherapy, Radiotherapy) Cancer treatment methods (Immunotherapy, Photodynamic therapy) Future Predictions in Cancer Treatment will be explained. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | What is cancer?
| | | Week 2 | Cancer morbidity and mortality in the world and in Turkey
| | | Week 3 | Key Differences of Cancer Cells from Healthy Cells | | | Week 4 | Cell Death Mechanisms
| | | Week 5 | Cell Cycle Control and Cancer
| | | Week 6 | DNA Repair Pathways in Cancer DNA Repair and Treatment | | | Week 7 | Tumor Suppressor Genes | | | Week 8 | Oncogenes | | | Week 9 | Mid exam | | | Week 10 | Biochemical Methods in Cancer Diagnosis and Follow-up | | | Week 11 | Discovery of New Biomarkers for Cancer Diagnosis and Treatment | | | Week 12 | Design, Development and Discovery of Anti-Cancer Drugs | | | Week 13 | Cancer treatment methods (Chemotherapy, Radiotherapy) | | | Week 14 | Cancer treatment methods (Immunotherapy, Photodynamic therapy) | | | Week 15 | Future Predictions in Cancer Treatment | | | Week 16 | Final Exam | | | |
| 1 | Jesse P. Greenstein Biochemistry of Cancer Academic Press 2013 978-1-4832-3140-2 | | | |
| 1 | Thomas Seyfried Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer 1st Edition,Wiley Press 2012 9781118310311 | | | 2 | Prof. Dr. Yusuf Baran Kanser Moleküler Biyolojisi Kısayol Yayıncılık 2018 978-605-2329-30-6 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 1 | 25.11.2023 | 1 | 50 | | End-of-term exam | 1 | 15.01.2024 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Arasınav için hazırlık | 2 | 7 | 14 | | Arasınav | 2 | 1 | 2 | | Dönem sonu sınavı için hazırlık | 5 | 5 | 25 | | Dönem sonu sınavı | 5 | 1 | 5 | | Total work load | | | 116 |
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