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| ECZ3039 | Lipids and Lİpoproteins | 2+0+0 | ECTS:4 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Prof. Dr. Sermet YILDIRMIŞ | | Co-Lecturer | Prof. Sermet YILDIRMIŞ | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | o examine the structure and function of lipids in detail, to understand the biochemical mechanisms that occur in lipid metabolism, to discuss lipid measurement methods, to teach the relationship between lipoproteins and coronary artery diseases. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Identify and classify lipids | 1,2,3,4 | | | LO - 2 : | Can explain fatty acids and their metabolism | 1,2,3,4 | | | LO - 3 : | Can explain phospholipids and their metabolism | 1,2,5 | | | LO - 4 : | Explain the structure and function of cholesterol | 1,2,4 | | | LO - 5 : | Can provide information about ketone bodies | 2,3,4 | | | LO - 6 : | Can explain lipoproteins | 3,5,6 | | | LO - 7 : | Can explain the relationship between lipoproteins and Atherosclerosis | 4,7,10,12 | | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| Classification and structural functions of lipids
Fatty acids and neutral oils
Phospholipids and Sphingolipids
Cholesterol and Bile acids
Ketone bodies synthesis and degradation
lipid metabolism
lipoproteins
Chylomicron metabolism
VLDL and LDL metabolism
HDL metabolism
Lipoproteins and Atherosclerosis |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | General information about lipids (definition, importance, structure and classification) | | | Week 2 | General information about fatty acids (structure, classification, types, importance, essential fatty acids, cyclic fatty acids, physical and chemical properties of fatty acids) | | | Week 3 | synthesis of fatty acids | | | Week 4 | Peta oxidation of fatty acids | | | Week 5 | General information about Lipoproteins | | | Week 6 | LDL metabolism | | | Week 7 | Chylomicron metabolism | | | Week 8 | Midterm | | | Week 9 | Phospholipids overview | | | Week 10 | Overview of sphingolipids | | | Week 11 | Information about membrane lipids | | | Week 12 | nformation about eicosanoids | | | Week 13 | Information about prostaglandins | | | Week 14 | cholesterol metabolism | | | Week 15 | Relationship between lipids and atherosclerosis | | | Week 16 | Final Exam | | | |
| 1 | Murray, R.K. (1993) Harper's Biochemistry, Appleton and Lange, Norwalk | | | |
| 1 | Nihat BAYŞU, Nalan Bayşu SÖZBİLİR.(2008) Biyokimya Güneş Tıp kitabevleri, 2008 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 1 | 28/11/2023 | | 50 | | End-of-term exam | 1 | 16/01/2024 | | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 14 | 2 | 28 | | Sınıf dışı çalışma | 3 | 2 | 6 | | Laboratuar çalışması | 3 | 2 | 6 | | Arasınav | 1 | 1 | 1 | | Uygulama | 3 | 5 | 15 | | Ödev | 3 | 4 | 12 | | Dönem sonu sınavı için hazırlık | 2 | 5 | 10 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 80 |
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