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| ECZ5033 | Vaccine Development and Vaccination | 2+0+0 | ECTS:4 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Prof. Dr. Atila Taner KALAYCIOĞLU | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The aim of vaccine development strategies for undergraduate program students is to introduce vaccines and vaccine development strategies that will be beneficial throughout their educational and professional life. During this course the basic immunology, the working mechanism of the immune system and vaccine development strategies will be taught to students. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | In the historical process, the development of vaccines and the implications for public health are learned. | 8,10 | 1, | | LO - 2 : | The immune response agains vaccines are learned. | 8,10 | 1, | | LO - 3 : | The protective immune mechansms gained by vaccines are learned. | 8,10 | 1, | | LO - 4 : | Information about vaccine types and vaccine immunogens are learned. | 8,10 | 1, | | LO - 5 : | Classical and new generation vaccine development strategies are learned. | 8,10 | 1, | | LO - 6 : | Childhood and adult vaccination programs are learned. | 8,10 | 1, | | LO - 7 : | The relationship between enfectious disease control and herd immunity are learned. | 8,10 | 1, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| The contents of course includes presentations and lectures. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Vaccine development and public health implications in historical process | | | Week 2 | Vaccine induced protective immune response | | | Week 3 | Vaccines and antigens | | | Week 4 | Live-attenuated and killed vaccines | | | Week 5 | Inactivated toxin and toxoid bacterial vaccines | | | Week 6 | Non-replicating virüs vaccines | | | Week 7 | Recombinant DNA technology and vaccines | | | Week 8 | Covid-19 vaccines and thier protective capacity | | | Week 9 | Midterm exam | | | Week 10 | Virus-like particles | | | Week 11 | Herd immunity and control of infectious diseases | | | Week 12 | Improving immunogenicity by including immune modulatory adjuvants | | | Week 13 | Improving immunogenicity by using next generation delivery systems | | | Week 14 | Emerging viral diseases and vaccine development strategies | | | Week 15 | Factors affecting vaccine efficacy and safety | | | Week 16 | End-of-term exam
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| 1 | Abul K. Abbas MBBS, Andrew H. H. Lichtman MD PhD, Shiv Pillai MD. 2014; Cellular and Molecular Immunology, 7th Edition with STUDENT CONSULT. ELSEVIER 2011ISBN-9781437715286 | | | 2 | David Male, Jonathan Brostoff, David B Roth, and Ivan M Roitt 2016; Immunology Eight Edition ELSEVIER2013 ISBN-13 9780323080583 | | | 3 | Stanley Plotkin Walter Orenstein Paul Offit Kathryn M. Edwards. 2017.: Plotkin's Vaccines 7th Edition, Elsevier, Hardcover ISBN: 9780323357616
eBook ISBN: 9780323393010
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| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | 30.11.2023 | 1 | 50 | | End-of-term exam | 16 | 20.01.2024 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 2 | 14 | 28 | | Arasınav için hazırlık | 2 | 7 | 14 | | Arasınav | 2 | 1 | 2 | | Ödev | 4 | 4 | 16 | | Dönem sonu sınavı için hazırlık | 2 | 7 | 14 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 104 |
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