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| ECZ3009 | metabolic relations and regulation | 2+0+0 | ECTS:4 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Prof. Dr. Arzu ÖZEL | | Co-Lecturer | - | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To examine the enzymatic, genetic and hormonal regulation mechanisms of these pathways with metabolic pathways, examine the diseases of carbohydrate, lipid and amino acid metabolism with the behavior of metabolism in abnormal conditions such as hunger and exercise. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | learn metabolic regulation with enzyme activity, control and regulation of enzyme reactions, | 1,2,8 | 1,5, | | LO - 2 : | discuss and compare controls of carbohydrate, lipids and nitrogen metabolisms with enzyme activities, | 1,2,8 | 1,5, | | LO - 3 : | discuss answers and adaptations strategy of metabolism to the extraordinary conditions such as starvation, thickness and exercise, | 1,2,8 | 1,5, | | LO - 4 : | classify disorders and metabolic diseases such as disorders of carbohydrate and amino acids metabolism, diseases of glycogen and lipid metabolism. | 1,2,8 | 1,5, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| Metabolic regulation, fasting, postprandial metabolic regulation in exercise conditions, some metabolic disorders and diseases |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | General view of metabolism and regulation, mechanisms of regulation and control | | | Week 2 | Metabolic regulation with enzymes, control and regulation of enzyme reactions | | | Week 3 | Control of carbohydrate metabolism with enzyme activity | | | Week 4 | Control of fatty acid metabolism with enzyme activity | | | Week 5 | Control of nitrogen metabolism with enzyme activity | | | Week 6 | Hormonal regulation of metabolism | | | Week 7 | Hormonal regulation of metabolism: receptors, types of receptor, hormones and metabolism | | | Week 8 | Midterm exam | | | Week 9 | Hormones affecting the regulation of metabolism | | | Week 10 | Adaptations of metabolism to extraordinary conditions: Starvation and metabolic answer, thickness and metabolic answer, exercise and metabolic answer | | | Week 11 | Metabolic disorders: disorders of carbohydrate metabolism, disorders of glycogen metabolism | | | Week 12 | Metabolic disorders: disorders of lipid metabolism, diseases of amino acid metabolism | | | Week 13 | Digestion and absorption | | | Week 14 | General evaluations and presentations | | | Week 15 | General evaluations and presentations | | | Week 16 | final | | | |
| 1 | Stryer Biyokimya | | | 2 | Lehninger Biyokimyanın İlkeleri | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 27/11/2023 | 2 | 50 | | Presentation | 9
10
11
12
13
14 | 4
11
18
25
/12/2023
01/01/2024 | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 14 | 2 | 28 | | Sınıf dışı çalışma | 2 | 10 | 20 | | Arasınav için hazırlık | 2 | 6 | 12 | | Arasınav | 1 | 2 | 2 | | Ödev | 4 | 6 | 24 | | Dönem sonu sınavı için hazırlık | 2 | 6 | 12 | | Dönem sonu sınavı | 1 | 2 | 2 | | Total work load | | | 100 |
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