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| CHM 452 | Biochemistry - III | 4+0+0 | ECTS:5 | | Year / Semester | Spring Semester | | Level of Course | First Cycle | | Status | Compulsory | | Department | DEPARTMENT of CHEMISTRY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 4 hours of lectures per week | | Lecturer | Prof. Dr. Nagihan SAĞLAM ERTUNGA | | Co-Lecturer | PROF. DR. Murat KÜÇÜK, | | Language of instruction | | | Professional practise ( internship ) | None | | | | The aim of the course: | | Gaining basic knowledge about identification of genetic information, gene expression, cooperativity of metabolism, control of metabolic pathways, vitamins, hormones, biotechnology, and bioengineering. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Students will understand the cooperativity in metabolic regulation | 1,2,3,4,5,6,7,8 | 1 | | LO - 2 : | Students will develop a basic understanding of gene expression, genetic heredity, and genome | 1,2,3,4,5,6,7,8 | 1 | | LO - 3 : | Students will learn structures and functions of vitamins and hormones | 1,2,3,4,5,6,7,8 | 1 | | LO - 4 : | Students will extend their background in biotechnology and bioengineering | 1,2,3,4,5,6,7,8 | 1 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| Structure and functions of nucleic acids, DNA, RNA, Genome, Gene structure and use in biosynthesis, Replication, Transcription, Translation, Post-translational modifications, Protein targeting, Differences between prokaryotes and eukaryotes in terms of gene expression, regulation of gene expression, General mechanisms in the regulation of metabolic pathways, cooperativity and coordination of metabolism, Structures of vitamins and their roles in metabolism, Structures and functions of hormones, Basic concepts in biotechnology, Fields of biotechnological applications, Bioengineering and subdivisions, Examples of bioengineering applications. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Structure and functions of nucleic acids | | | Week 2 | DNA, RNA, Genome, Gene structure and use in biosynthesis | | | Week 3 | Replication | | | Week 4 | Transcription | | | Week 5 | Translation, Post-translational modifications, Protein targeting | | | Week 6 | Differences between prokaryotes and eukaryotes in terms of gene expression, regulation of gene expression | | | Week 7 | General mechanisms in the regulation of metabolic pathways, cooperativity and coordination of metabolism | | | Week 8 | Structures of vitamins and their roles in metabolism | | | Week 9 | Midterm | | | Week 10 | Structures and functions of hormones | | | Week 11 | Basic concepts in biotechnology | | | Week 12 | Fields of biotechnological applications | | | Week 13 | Bioengineering and subdivisions | | | Week 14 | Examples of bioengineering applications | | | Week 15 | Examples of bioengineering applications | | | Week 16 | Final exam | | | |
| 1 | Albert Lehninger, David L. Nelson, Michael M. Cox, Lehninger Principles of Biochemistry (5.Ed.), W. H. Freeman, 2008. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 08.04.2016 | 1 | 50 | | End-of-term exam | 16 | 03.06.2016 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 4 | 14 | 56 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Arasınav için hazırlık | 12 | 1 | 12 | | Arasınav | 2 | 1 | 2 | | Ödev | 5 | 1 | 5 | | Dönem sonu sınavı için hazırlık | 12 | 1 | 12 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 131 |
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