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| DPI 622 | Pathogenesis of Periodontal Diseases | 1+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Third Cycle | | Status | Compulsory | | Department | DEPARTMENT of PERIODONTOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 1 hour of lectures per week | | Lecturer | Prof. Dr. Esra BALTACIOĞLU | | Co-Lecturer | Prof. Dr. Adnan TEZEL | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | To inform the students about pathogenesis of periodontal diseases, to teach effects on the periodontal pathogenesis mechanisms. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | know the gingival inflammation.
| 1,2,9,10,11,13,18,19,20 | 1 | | PO - 2 : | know the development of periodontal diseases.
| 1,2,9,10,11,13,20 | 1 | | PO - 3 : | know the factors of the effect the periodontal pathogenesis.
| 1,2,9,10,11,13,20 | 1 | | PO - 4 : | know the cells of immunity and inflammation . | 1,2,4,9,10,11,13,20 | 1 | | PO - 5 : | know the immunoglobulins,cytokines and effect of cytokines. | 1,2,9,11,13,20 | 1 | | PO - 6 : | know the T cells response and B cells response, immun response. | 11,13 | 1 | | PO - 7 : | know the gingival inflamation's stages. | 1,2,9,11,13,20 | 1 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Gingival inflammation development of periodontal diseases.
Bone destruction patterns.
Identification of periodontal pathogenesis and the factors affecting the pathogenesis.
Role of the bacterial plaque on periodontal pathogenesis.
Cells of immunity and inflammation (mast cells, dermal dendrocytes, peripheral dendritic cells, neutrophills and monocytes/macrophages, lymphocytes, T cells, B cells, NK cells), complement, leukocytes functions.
Immunoglobulines,cytokines and enzymatic mechanisms (Matrix metalloproteinases).
The effects of genetic and systemic risk factors on periodontal pathogenesis ( systemics disorders, smoke, stress, medicines, nutrition).
The effects of local risk factors on periodontal pathogenesis (occlusal travma, parafunctions, mechanic and chemical stimulations).
Immun responses ( spesific and non specific immun responses).
Connective tissue and bone metabolism.
Gingival inflammation (The Initial lesion, The Early lesion, The Established lesion, The Advanced lesion ) . |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Identification of periodontal pathogenesis and effect on the periodontal pathogenesis factors. | | | Week 2 | Role of the bacterial plaque on periodontal pathogenesis. | | | Week 3 | Cells of immunity and inflammation(mast cells,dermal dendrocytes, peripheral dendritic cells, neutrophills and monocytes/macrophages). | | | Week 4 | Cells of immunity and inflammation (lymphocytes, T cells, B cells , NK cells),complement,leukocytes functions. | | | Week 5 | Immunoglobulins, cytokines and effect of cytokines. | | | Week 6 | Enzymatics mechanisms (Matrix metalloproteinases). | | | Week 7 | Genetic risk factors, diseases and defects effects on periodontal pathogenesis. | | | Week 8 | Mid-term exam. | | | Week 9 | Systemics changeable risk factors effects of periodontal pathogenesis (systemics disorders, smoke, stress, medicines, nutrition). | | | Week 10 | Local changeable risk factors effects of periodontal pathogenesis (saliva, occlusal trauma, parafunctions, mechanic and chemical stimulations). | | | Week 11 | Immun responses (spesific and non specific immun responses), T cell and B cell responses. | | | Week 12 | Host responses. | | | Week 13 | Connective tissue and bone metabolism. | | | Week 14 | Gingival inflammation (The initial lesion, The Early lesion ). | | | Week 16 | End-of-term exam. | | | |
| 1 | Newman MG. , Takei HH. , Klokkevold PR. , Carranza FA. , 2006; Carranza's Clinical Periodontology, Tenth edition, WB Saunders Company. | | | 2 | Lindhe J. , Lang NP. , Karring T. , 2008; Clinical Periodontology and Implant Dentistry, 5th Edition. Wiley-Blackwell. | | | 3 | Rose LF. , Mealey B. , Genco R. , 2004; Periodontics, 1th edition, St. Louis. | | | |
| 1 | Neville B. , Douglas DD. , Allen CM. , Bouquot J. , 2008; Oral and Maxillofacial Pathology, 3th edition, St. Louise. | | | 2 | Little JW., Falace D. , Miller C., Rhodus NL. ,2007; Dental Management of the medically Compromised Patient, 7.edition, St. Louise. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | 15/11/2009 | 1 | 50 | | End-of-term exam | 16 | 22/06/2010 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | | | | |
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