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| ECZ3044 | Polymers and Their Use in Drug Delivery Systems | 2+0+0 | ECTS:4 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Prof. Dr. Dilek KUL | | Co-Lecturer | | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | This course aims to provide fundamental information on polymer chemistry in the fields of medicine, cosmetics, and pharmacy, including polymer terminology, polymerization mechanisms and methods, properties of polymers, and some specific polymers in medicine and pharmacy and their applications in these fields. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Use the terminology of polymer correctly. | 4 - 6 - 10 | 1,3, | | LO - 2 : | Know polymerization mechanisms and methods. | 4 - 6 - 10 | 1,3, | | LO - 3 : | Know the types of polymers and their unique properties. | 4 - 6 - 10 | 1,3, | | LO - 4 : | Knows the polymers commonly used in medicine and pharmacy and their usage methods, and can both use and transfer their knowledge to others. | 4 - 6 - 10 | 1,3, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| Fundamental concepts in polymer science (classification, molecular weight, glass transition temperature, melting point, etc.), mechanical and thermal properties of polymers, polymerization methods, polymerization systems, copolymerization, gelation, biomaterials, bioerodible and non-erodible polymers, hydrogels, polymeric drug delivery polymers, and applications of polymers in drug delivery systems.
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | What is a Polymer?, Natural and Synthetic Polymers, Representation and Sequence of Polymer Chains, Molecular Weight Calculation in Polymers, Heterogeneity Index | | | Week 2 | Thermal Properties of Polymers (glass transition temperature and melting point), Natural polymer (latex), Polymers and textiles, Hair and polymer, Self-flowing polymer, Ink and polymers | | | Week 3 | Polymerization Methods, Condensation Polymerization (catalyst and mechanism), Gelation Phenomenon, Cross-linked Polymers and Degree of Swelling | | | Week 4 | Addition Polymerization and Its Types, Properties of Addition and Condensation Polymerization, Anionic Polymerization (catalysts and mechanism) | | | Week 5 | Cationic Polymerization (catalysts, mechanism, influencing factors), Free radical polymerization (initiators, inhibitors, retarders, and mechanism) | | | Week 6 | Bulk, Solution, Emulsion and Suspension Polymerization Systems, Copolymerization | | | Week 7 | Classification of polymers according to the source of compounds, the way the chain is constructed, thermally, according to the repeating unit, etc., Advantages and Disadvantages of Polymers over Metals, Some Important Polymers and Their Areas of Use, Plastic Fillers | | | Week 8 | Biomaterials, properties, classification, biological compatibility tests and physical properties of biomaterials | | | Week 9 | Mid-term Exam | | | Week 10 | Classification of Biomaterial Polymers, Non-Bioerodible Polymers, Bioerodible (Biodegradable) Polymers | | | Week 11 | Some Biodegradable Polymers and Their Uses in Pharmaceuticals | | | Week 12 | Some Biodegradable Polymers and Their Uses in Pharmaceuticals | | | Week 13 | Hydrogels and Their Applications in Pharmaceuticals | | | Week 14 | Natural Polymers for Drug Delivery Systems, Natural Polymers for Drug Delivery Systems | | | Week 15 | Drug Carrier Forms in Drug Delivery Systems, Applications of Polymers in Drug Delivery Systems | | | Week 16 | Final Exam | | | |
| 1 | Polymer Science and Technology, J.R. Fried, Prentice Hall, NJ, 2003. | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 08/04/2026 | 1 | 50 | | End-of-term exam | 16 | 08/06/2026 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Arasınav için hazırlık | 4 | 8 | 32 | | Arasınav | 2 | 1 | 2 | | Dönem sonu sınavı için hazırlık | 6 | 6 | 36 | | Dönem sonu sınavı | 2 | 1 | 2 | | Total work load | | | 100 |
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