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| ECZ4009 | Pharmacology - IV | 2+0+0 | ECTS:3 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Compulsory | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Dr. Öğr. Üyesi Serhat SEVGİ | | Co-Lecturer | Assistant Professor Yeşim K. YAŞAR | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | |
The objective of this course is to provide students with a comprehensive understanding of the endocrine system and endogenous autacoids, and to explain the mechanisms of action, therapeutic uses, contraindications, and adverse effects of drugs that affect these systems. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | Understand the physiology of the endocrine system | 6 - 7 | 1 | | LO - 2 : | Know the classification and pharmacodynamics of the drugs affecting endocrine system | 6 - 7 | 1 | | LO - 3 : | Know the classification and pharmacodynamics of the drugs affecting respiratory system | 6 - 7 | 1 | | LO - 4 : | Understand the classification, basic function of the autocoids and related drugs | 6 - 7 | 1 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| An introduction to the pharmacology of the endocrine system; the physiology of thyroid hormones (T3, T4, TSH) and the mechanisms of action of thyroid medications; hormones regulating calcium and phosphorus metabolism (parathyroid hormone, calcitonin, vitamin D) and calciotropic drugs; the pharmacology of pancreatic hormones (insulin, glucagon) and antidiabetic drugs; the pharmacological properties of adrenal cortex hormones (ACTH, glucocorticoids, mineralocorticoids) and their acting drugs; the mechanisms of action, therapeutic uses, and side effects of gonadal hormones (estrogen, progestin, androgens) and related drugs; and the pharmacological effects of autacoids and other regulatory compounds related to the endocrine system. The course covers the holistic functioning of the endocrine system, hormonal regulation mechanisms, and the clinical outcomes of pharmacological interventions. |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Introduction to endocrine system pharmacology | | | Week 2 | Thyroid gland, hormones, disorders and drugs | | | Week 3 | Pancreatic hormones (insulin, glucagon) | | | Week 4 | Diabetes and antidiabetic drugs | | | Week 5 | Hormones that regulate calcium and phosphorus metabolism (calcitonin, parathyroid hormone, vitamin D) & Drugs | | | Week 6 | OCTOBER 29 Turkish REPUBLIC DAY (Holiday) | | | Week 7 | Calciotropic drugs | | | Week 8 | ACTH and Corticosteroids
Glucocorticoids and mineralocorticoid drugs-1 | | | Week 9 | Mid term exam | | | Week 10 | Glucocorticoids and mineralocorticoid drugs-2 | | | Week 11 | Gonadal hormones-1: Estrogen | | | Week 12 | Gonadal hormones-2: Progestin | | | Week 13 | Gonadal hormones-3: Androgens | | | Week 14 | Gonadal hormones-4: Other hormones and drugs | | | Week 15 | Autocoids | | | Week 16 | Final exam | | | |
| 1 | Kayaalp, O. 2022. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji (14. baskı). Pelikan Yayıncılık, Ankara. | | | |
| 1 | Rang, H.P., Dale, M.M., Ritter, J.M., Flower, R.J., Henderson, G. 2021; Rang & Dales Pharmacology, 10th Edition, Elsevier, London | | | 2 | Katzung, B.G., Vanderah, T.W. 2021; Basic and Clinical Pharmacology, 16th Edition, McGraw-Hill Education, New York. | | | 3 | Brunton, L.L., Hilal-Dandan, R., Knollmann, B.C. 2023; Goodman & Gilman?s The Pharmacological Basis of Therapeutics, 14th Edition, McGraw-Hill Education, New York. | | | 4 | Model List of Essential Medicines and Guidelines for Hormonal and Endocrine Disorders Treatment. https://www.who.int/publications | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | Kasım 2025 | 1 saat | 50 | | End-of-term exam | 16 | Ocak 2025 | 1 saat | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Arasınav | 1 | 1 | 1 | | Dönem sonu sınavı | 1 | 1 | 1 | | Total work load | | | 30 |
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