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ECZ2037Molecular Biology2+0+0ECTS:4
Year / SemesterFall Semester
Level of CourseSecond Cycle
Status Elective
DepartmentDEPARTMENT of PHARMACEUTICS
Prerequisites and co-requisitesNone
Mode of Delivery
Contact Hours14 weeks - 2 hours of lectures per week
LecturerProf. Dr. Rezzan ALİYAZICIOĞLU
Co-Lecturer
Language of instructionTurkish
Professional practise ( internship ) None
 
The aim of the course:
To provide an understanding of the organization and nature of genetic material, replication, genetic material transfers, change and control mechanisms of gene expression.
 
Learning OutcomesCTPOTOA
Upon successful completion of the course, the students will be able to :
LO - 1 : Be able to describe the structures and properties of nucleic acids1 - 8 - 10
LO - 2 : Explain the organization and expression of genes.1 - 8 - 10
LO - 3 : Explain replication, mutations and repair of DNA.1 - 8 - 10
LO - 4 : Know the principles of nucleic acid analysis methods1 - 8 - 10
CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome

 
Contents of the Course
Systems and methods of molecular biology, macromolecular interactions, DNA technology, DNA replication, repair, mutation, transcription and translation, gene regulation, genetic engineering, oncogenes and cancer
 
Course Syllabus
 WeekSubjectRelated Notes / Files
 Week 1Definition and importance of molecular biology
 Week 2Structure of nucleic acids
 Week 3Replication of DNA
 Week 4Transcription
 Week 5Translation
 Week 6Structure of function proteins
 Week 7Mutations
 Week 8DNA repair mechanism
 Week 9Mid term
 Week 10Technology of nucleic acid
 Week 11Genetic analysis of molecular biology
 Week 12Techniques used in Molecular Biology (DNA electrophoresis, protein electrophoresis)
 Week 13Techniques used in Molecular Biology (western blotting, southern blotting)
 Week 14Recombinant DNA technology
 Week 15Oncogens
 Week 16Final exam
 
Textbook / Material
 
Recommended Reading
1Molecular Biology, David Freifelder, Jones and Barlett Publishers Inc Boston, USA, 1985, Molecular Biology, Second Edition, Robert F. Weaver Mc Graw-Hill 2003.
 
Method of Assessment
Type of assessmentWeek NoDate

Duration (hours)Weight (%)
Mid-term exam 9 21/11/2023 1 50
End-of-term exam 16 19/01/2024 1 50
 
Student Work Load and its Distribution
Type of workDuration (hours pw)

No of weeks / Number of activity

Hours in total per term
Yüz yüze eğitim 2 14 28
Sınıf dışı çalışma 1 14 14
Arasınav için hazırlık 2 8 16
Arasınav 1 1 1
Ödev 4 6 24
Proje 4 6 24
Dönem sonu sınavı için hazırlık 1 6 6
Dönem sonu sınavı 1 1 1
Total work load114