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| ECZ2005 | Vitamins and Coenzymes | 2+0+0 | ECTS:4 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of PHARMACEUTICS | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | Prof. Dr. Rezzan ALİYAZICIOĞLU | | Co-Lecturer | none | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | learn to fat and water soluble vitamins, enzymes and metabolic functions |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | metabolism of vitamin A | 1 - 2 - 8 | 1, | | LO - 2 : | Metabolism of vitamin D and metabolic functions | 1 - 2 - 8 | 1, | | LO - 3 : | Biosynthesis of vitamin E and K, metabolism | 1 - 2 - 8 | 1, | | LO - 4 : | metabolic functions of flavin coenzymes | 1 - 2 - 8 | 1, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| introduction and classicifitation of vitamins,
synthesis, metabolic functions of vitamin A, D,E,K
synthesis, metabolic functions of B1, B2, B3, B5, B6, B12 vitamins and coenzymes, innovative approaches |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Vitamin Overview | | | Week 2 | metabolic functions of Vitamin A and deficiency | | | Week 3 | metabolic functions, metabolism,synthesis of Vitamin A and deficiency | | | Week 4 | Vitamin K-dependent proteins, disability,
metabolic functions of tiamin bisphosphate | | | Week 5 | Nicotinamide nucleotide coenzymes | | | Week 6 | Vitamin B6 absorption and metabolism | | | Week 7 | Folate biosynthesis and metabolism | | | Week 8 | Biotin metabolism, biotin-dependent carboxylase, inadequacy | | | Week 9 | intermediate exam | | | Week 10 | hydroxylase containing copper | | | Week 11 | prevention of nitrosamine formation | | | Week 12 | Acyl carrier protein | | | Week 13 | Megaloblastic anemia | | | Week 14 | pharmacological use of flavin coenzymes | | | Week 15 | cancer treatment and prevention | | | Week 16 | final exam | | | |
| 1 | Nelson, D.L., Cox, M.M. , 2005. Lehninger Principles of Biochemistry, W.H. Freeman and Company, New York | | | 2 | Keha, E., Küfrevioğlu, Ö.İ. 2004; Biyokimya, Aktif Yayınevi, Ankara | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 18/11/2025 | 1 | 50 | | End-of-term exam | 16 | 15/01/2026 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 3 | 14 | 42 | | Arasınav için hazırlık | 3 | 8 | 24 | | Arasınav | 1 | 1 | 1 | | Ödev | 1 | 1 | 1 | | Dönem sonu sınavı için hazırlık | 4 | 5 | 20 | | Dönem sonu sınavı | 1 | 1 | 1 | | Total work load | | | 117 |
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