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| BIY4011 | Human Genetics | 3+0+0 | ECTS:5 | | Year / Semester | Fall Semester | | Level of Course | First Cycle | | Status | Elective | | Department | DEPARTMENT of BIOLOGY | | Prerequisites and co-requisites | None | | Mode of Delivery | | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Remziye NALÇACIOĞLU | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The main objectives of this course are to provide the student with a clear presentation of the basic concepts and principles of related subjects. |
| Learning Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | LO - 1 : | can know human genome information | 1 - 2 | 1, | | LO - 2 : | talk about the inheritance of some human characteristics | 1 - 2 | 1, | | LO - 3 : | talk on Caryotype and idiogram of human chromosomes | 1 - 2 | 1, | | LO - 4 : | know the chromosomal abnormalities and the diseases caused with these abnormalities | 1 - 2 | 1, | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome | | |
| 1 ? Introduction to Human Genetics
2 ? Genetic Material; structure, replication, transcription, translation
3 ? Chromosomes
4 ? Mutations
5 ? Methods of studying genetic factors
6 ? Dermatoglyphs
7 ? Inheritance patterns
8 ? Examples of normal and polygenic inheritance
9 ? Down Syndrome ? Turner Syndrome ? Klinefelter Syndrome ? Alzheimer's Syndrome ? Parkinson's Syndrome ? Sickle Cell Anemia ? Thalassemia
10 ? Immunogenetics
11 ? Triple Nucleotide Repeats
12 ? Human Genome Project
13 ? Gene Therapy
14 ? Cancer
15 ? Stem cells
16 ? Recombinant DNA technology
17 ? SNP analyses
18 ? Diagnosis from genetic analyses
19 ? Consanguineous marriages |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Structure of genetic material
| | | Week 2 | Methods of examining genetic parameters
| | | Week 3 | Inherited properties and inherited patterns
| | | Week 4 | Non mendelian heredity
| | | Week 5 | Normal and polygeneic heredity | | | Week 6 | Dermatoglyphics and sitogenetic | | | Week 7 | Gene mapping and human genome project
| | | Week 8 | Genetic variations in humans | | | Week 9 | Mid-term exam | | | Week 10 | Otosomal and gonosomal diseases in humans
| | | Week 11 | Molecular and biochemical principles of genetic diseases
| | | Week 12 | Otosomal and gonosomal diseases in humans
| | | Week 13 | student presentations | | | Week 14 | Therapy of hereditary diseases | | | Week 15 | Genetics of immun system | | | Week 16 | End-of-term exam | | | |
| 1 | Başaran, N. 1999; Tıbbi Genetik, Güneş ve nobel Tıp Kitapevi, İstanbul
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| 1 | Nussbaum, R.L., McInnes, R.R., Willard, H.F. 2005; Thompson ve Thompson Tıbbi Genetik, Güneş Kitavevi, Ankara/İstanbul | | | 2 | Klug, W.S., Cummings, M.R., Spencer, C.A. (Çeviri Baş Editör; Cihan Öner), 2009; Genetik Kavramlar, Palme Yayıncılık, Ankara
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| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 9 | 22/11/2015 | 1 | 50 | | End-of-term exam | 16 | 13/01/2016 | 1 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 13 | 39 | | Sınıf dışı çalışma | 5 | 14 | 70 | | Arasınav için hazırlık | 1 | 7 | 7 | | Arasınav | 1 | 1 | 1 | | Dönem sonu sınavı için hazırlık | 4 | 7 | 28 | | Dönem sonu sınavı | 1 | 1 | 1 | | Diğer 1 | 2 | 2 | 4 | | Total work load | | | 150 |
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