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| BIO 522 | Enzymology | 2+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of MEDICAL BIOCHEMISTRY | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 2 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | The course aims to provide the students with a general knowledge on enzymes. |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | know enzymes | 1,2 | 1,3 | | PO - 2 : | learn mechanism of enzyme action | 1,2 | 1,3 | | PO - 3 : | know enzyme kinetics | 1,2 | 1,3 | | PO - 4 : | follow studies on enzymes | 1,2 | 1,3 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Introduction to enzymesClassification of enzymesHow enzymes workInhibition and activationAllosteric enzymesSome enzymatic reactions Enzyme Kinetics |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | General structures of enzymes | | | Week 2 | General structures of enzymes | | | Week 3 | Coenzymes | | | Week 4 | Properties of enzymes | | | Week 5 | Isoenzymes | | | Week 6 | Enzyme kinetics | | | Week 7 | Enzyme kinetics | | | Week 8 | Mid-term exam | | | Week 9 | Regulation of enzymatic reactions | | | Week 10 | Regulation of enzymatic reactions | | | Week 11 | Regulation of enzymatic reactions | | | Week 12 | Inhibition | | | Week 13 | Allosteric enzymess | | | Week 14 | Allosteric enzymes | | | Week 16 | End-of-term exam | | | |
| 1 | Nelson DL, Cox, MM:2000;Lehninger Principles of Biochemistry, Worth Publ.,New York | | | |
| 1 | Bhagavan, NV.2002;Medical Biochemistry, Academic Press, San Diego | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | | 2 | 30 | | Homework/Assignment/Term-paper | 12 | | 4 | 20 | | End-of-term exam | 17 | | 3 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 2 | 14 | 28 | | Sınıf dışı çalışma | 4 | 14 | 56 | | Arasınav için hazırlık | 30 | 1 | 30 | | Arasınav | 2 | 1 | 2 | | Dönem sonu sınavı için hazırlık | 30 | 1 | 30 | | Dönem sonu sınavı | 3 | 1 | 3 | | Total work load | | | 149 |
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