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| EBK5203 | knowledge of enzyme | 3+0+0 | ECTS:7.5 | | Year / Semester | Spring Semester | | Level of Course | Second Cycle | | Status | Compulsory | | Department | DEPARTMENT of BIOCHEMISTRY (PHARMACY) | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | Prof. Dr. Oktay YILDIZ | | Co-Lecturer | None | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | This lecture aims to provide students with the fundamentals of enzyme chemistry |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | Know enzymes and their cofactors | 3,8,10 | 1,3 | | PO - 2 : | Learn enzyme kinetics | 3,8,10 | 1,3 | | PO - 3 : | Make comments on enzyme inhibitions | 3,8,10 | 1,3 | | PO - 4 : | Determine enzyme reaction mechanisms | 3,8,10 | 1,3 | | PO - 5 : | Remember enzyme activity determination techniques | 3,8,10 | 1,3 | | PO - 6 : | Percieve enzyme activity regulations | 3,8,10 | 1,3 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| The lecture covers the structures and functions of enzymes, enzyme inhibition, the factors affecting enzyme activity and the determination metods of enzyme activity
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Enzymes | | | Week 2 | Cofactors | | | Week 3 | Enzyme specificy | | | Week 4 | Enzyme kinetics | | | Week 5 | Enzyme inhibition | | | Week 6 | Enzyme reaction mechanisms | | | Week 7 | The factors affecting enzyme activity | | | Week 8 | The determination methods for enzyme activity | | | Week 9 | Midterm Examination | | | Week 10 | Multienzyme systems | | | Week 11 | Allosteric enzymes | | | Week 12 | Izoenzymes (izozymes) | | | Week 13 | The regulation of enzyme activity | | | Week 14 | Immobilised enzymes | | | Week 15 | Immobilised enzymes | | | Week 16 | Final | | | |
| 1 | Nelson David, Cox Michaelis, Lehninger Biyokimyanin İlkeleri, Palme Yayıncılık, Ankara. | | | 2 | Berman M and Marks A. Basic medical biochemistry, lippincott, 2009 | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 2 | 04.2024
05.2024 | 4 | 50 | | End-of-term exam | 1 | 06.2024 | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 3 | 14 | 42 | | Sınıf dışı çalışma | 3 | 10 | 30 | | Laboratuar çalışması | 2 | 10 | 20 | | Arasınav için hazırlık | 3 | 14 | 42 | | Arasınav | 2 | 2 | 4 | | Uygulama | 2 | 5 | 10 | | Klinik Uygulama | 3 | 5 | 15 | | Ödev | 2 | 5 | 10 | | Proje | 2 | 10 | 20 | | Dönem sonu sınavı için hazırlık | 10 | 2 | 20 | | Dönem sonu sınavı | 2 | 1 | 2 | | Diğer 1 | 3 | 5 | 15 | | Total work load | | | 230 |
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