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| EBK5206 | Nucleic acid metabolism | 3+0+0 | ECTS:7.5 | | Year / Semester | Fall Semester | | Level of Course | Second Cycle | | Status | Elective | | Department | DEPARTMENT of BIOCHEMISTRY (PHARMACY) | | Prerequisites and co-requisites | None | | Mode of Delivery | Face to face | | Contact Hours | 14 weeks - 3 hours of lectures per week | | Lecturer | -- | | Co-Lecturer | Arzu Özel, Rezzan Aliyazıcıoğlu | | Language of instruction | Turkish | | Professional practise ( internship ) | None | | | | The aim of the course: | | Learn the structure and metabolism of nucleic acids |
| Programme Outcomes | CTPO | TOA | | Upon successful completion of the course, the students will be able to : | | | | PO - 1 : | explain the structure of nucleic acids
| 1,8,10 | 1,3 | | PO - 2 : | tell the functions of nucleic acids
| 1,8,10 | 1,3 | | PO - 3 : | describe the synthesis of DNA and RNA | 1,8,10 | 1,3 | | CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), PO : Learning Outcome | | |
| Structure and Functions of nucleotides, nucleotide metabolism, DNA structure and its RNA Structure and DNA synthesis, RNA synthesis, protein synthesis |
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| Course Syllabus | | Week | Subject | Related Notes / Files | | Week 1 | Purine and pyrimidine bases | | | Week 2 | nucleic acids
| | | Week 3 | Nucleic acid functions | | | Week 4 | Nucleic acid metabolism | | | Week 5 | The synthesis of purine and pyrimidine nucleotides | | | Week 6 | Degradation of purines and pyrimidines | | | Week 7 | Nucleic acid metabolism disorders | | | Week 8 | mid-term exam | | | Week 9 | DNA structure | | | Week 10 | DNA synthesis
DNA recombination | | | Week 11 | RNA structure | | | Week 12 | RNA synthesis
| | | Week 13 | mutations | | | Week 14 | Repair of damaged DNA | | | Week 15 | DNA recombination | | | Week 16 | Final Exam | | | |
| 1 | Bhagavan, N.V. 2002; Medical Biochemistry, Academic Press, Fourth Edition, Canada | | | |
| 1 | Burtis, A.B., Achwood, E.R., Bruns, D.E. 2006; TIETZ Textbook of Clinical Chemistry and Molecular Diagnostics,Elsevier Inc. USA | | | |
| Method of Assessment | | Type of assessment | Week No | Date | Duration (hours) | Weight (%) | | Mid-term exam | 8 | 13/11/2017 | 1 | 50 | | End-of-term exam | 16 | 08/01/2018 | 2 | 50 | | |
| Student Work Load and its Distribution | | Type of work | Duration (hours pw) | No of weeks / Number of activity | Hours in total per term | | Yüz yüze eğitim | 14 | 3 | 42 | | Arasınav için hazırlık | 5 | 2 | 10 | | Arasınav | 1 | 1 | 1 | | Ödev | 2 | 2 | 4 | | Dönem sonu sınavı için hazırlık | 5 | 2 | 10 | | Dönem sonu sınavı | 1 | 2 | 2 | | Total work load | | | 69 |
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