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FACULTY of PHARMACY / DEPARTMENT of PHARMACEUTICS

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FACULTY of PHARMACY / DEPARTMENT of PHARMACEUTICS /
Katalog Ana Sayfa
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ECZ3047Clinical Chemisrty2+0+0ECTS:2
Year / SemesterFall Semester
Level of CourseSecond Cycle
Status Compulsory
DepartmentDEPARTMENT of PHARMACEUTICS
Prerequisites and co-requisitesNone
Mode of Delivery
Contact Hours14 weeks - 2 hours of lectures per week
LecturerDr. Öğr. Üyesi Merve BADEM
Co-LecturerAssoc.Prof.Rezzan ALİYAZICIOĞLU, Assist.Prof.Sermet YILDIRMIŞ
Language of instructionTurkish
Professional practise ( internship ) None
 
The aim of the course:
Provide general information on the principle of scientific and technological test about clinical biochemistry
 
Learning OutcomesCTPOTOA
Upon successful completion of the course, the students will be able to :
LO - 1 : Explain what is the biochemical samples. 4,5,6,8
LO - 2 : Sort importance of enzymes in the clinical diagnosis. 4,5,6,8
LO - 3 : Sort importance of carbohydrate in the clinical diagnosis.4,5,6,8
LO - 4 : Sort kidney function tests. 4,5,6,8
LO - 5 : Define plasma lipids and atherosclerosis and sort their importance. 4,5,6,8
LO - 6 : Know how to use plasma proteins in the clinic. 4,5,6,8
LO - 7 : Give information about blood biochemistry. 4,5,6,8
LO - 8 : Give information about urine tests. 4,5,6,8
LO - 9 : Sort the liver function tests. 4,5,6,8
CTPO : Contribution to programme outcomes, TOA :Type of assessment (1: written exam, 2: Oral exam, 3: Homework assignment, 4: Laboratory exercise/exam, 5: Seminar / presentation, 6: Term paper), LO : Learning Outcome

 
Contents of the Course
Biochemical Samples: Blood, Urine, Stool, Collecting of Cerebrospinal Fluid, Stabilization and Storage of Samples, Preanalytical Factors: Controlled and Uncontrolled Biological Factors, The Importance of Enzymes in Clinical Diagnosis: Description of the Enzyme, Targets of Enzyme Assay , The Importance of Plasma Proteins in Clinical Diagnosis: Hypoproteinemia, Serum Total Protein, Albumin, Ceruloplasmin, Transferrin, ?-1-acib Glycoprotein, Disorders of Carbohydrate Metabolism : Regulation of Blood Glucose Concentration, Plasma Lipids and Atherosclerosis: The General Structure and Function of Lipoproteins, Plasma Lipoprotein Disorders, Kidney Function Tests: Tubular Function, Water Reabsorption, The Biochemical Basis of Kidney Diseases, Liver Function Tests: Liver Function, Biochemical Tests, Bile, Gall Stones, Iron Metabolism and Anemia: Transferrin and Total Iron Binding Capacity, Plasma Ferritin Concentrations
 
Course Syllabus
 WeekSubjectRelated Notes / Files
 Week 1The History of Clinical Biochemistry, Biochemical Samples: Blood, Urine, Collecting of Cerebrospinal Fluid, Stabilization and Storage of Samples
 Week 2Preanalytical Factors: Controlled and Uncontrolled Biological Factors
 Week 3The Importance of Enzymes in Clinical Diagnosis: Description of the Enzyme, Targets of Enzyme Assay
 Week 4The Importance of Plasma Proteins in Clinical Diagnosis: Hypoproteinemia, Serum Total Protein, Albumin, Ceruloplasmin, Transferrin
 Week 5Disorders of Carbohydrate Metabolism : Regulation of Blood Glucose Concentration
 Week 6Plasma Lipids and Atherosclerosis: The General Structure and Function of Lipoproteins, Plasma Lipoprotein Disorders
 Week 7Kidney Function Tests: Tubular Function, Water Reabsorption, The Biochemical basis of Kidney Diseases
 Week 8Blood Biochemistry
 Week 9Midterm exam
 Week 10Urine Biochemistry
 Week 11Liver Function Tests: Biochemical Tests, Bile, Gall Stones
 Week 12Iron Metabolism and Anemia: Transferrin and Total Iron Binding Capacity, Plasma Ferritin Concentrations
 Week 13Minerals and Bone Metabolism: Sodium, Potassium, Chloride, Calcium, Magnesium
 Week 14Minerals and bone metabolism: Sodium, potassium, chloride, calcium, magnesium
 Week 15Endocrinology
 Week 16Final Exam
 
Textbook / Material
1Burtis CA, Ashwood ER: Tietz Textbook of Clinical Chemistry, USA: W.B. Saunders Company, 1994.
2Stryer L. Biochemistry, ed 3. New York: WH Freeman, 1988.
3Murray RK, Granner DK, Mayes PA and Rodwell WW. Harper?s Biochemistry, Stamford: Appleton. Lange, 1996.
 
Recommended Reading
 
Method of Assessment
Type of assessmentWeek NoDate

Duration (hours)Weight (%)
Mid-term exam 9 21/11/2021 1 50
End-of-term exam 16 23/01/2022 1 50
 
Student Work Load and its Distribution
Type of workDuration (hours pw)

No of weeks / Number of activity

Hours in total per term
Yüz yüze eğitim 2 14 28
Sınıf dışı çalışma 3 10 30
Arasınav için hazırlık 2 1 2
Arasınav 3 5 15
Dönem sonu sınavı 3 2 6
Total work load81